Now showing items 1-4 of 4
4d-qsar study of hept derivatives by electron conformational-genetic algorithm method
(Taylor & Francis Ltd, 2012)
In this work, the EC-GA method, a hybrid 4D-QSAR approach that combines the electron conformational (EC) and genetic algorithm optimization (GA) methods, was applied in order to explain pharmacophore (Pha) and predict ...
Application of electron conformational-genetic algorithm approach to 1,4-dihydropyridines as calcium channel antagonists: pharmacophore identification and bioactivity prediction
Two different approaches, namely the electron conformational and genetic algorithm methods (EC-GA), were combined to identify a pharmacophore group and to predict the antagonist activity of 1,4-dihydropyridines (known ...
4D-QSAR analysis and pharmacophore modeling: Electron conformational-genetic algorithm approach for penicillins
(Pergamon-Elsevier Science Ltd, 2011)
4D-QSAR studies were performed on a series of 87 penicillin analogues using the electron conformational-genetic algorithm (EC-GA) method. In this EC-based method, each conformation of the molecular system is described by ...
Diterpenoids from Sideritis tmolea P. H. Davis
(Acg Publications, 2007)
Four known ent-kaurene diterpenoids 1-4 were isolated from the acetone extract of Sideritis tmolea P. H. Davis by using different chromatographic methods. The structures of the isolated compounds were determined as siderol ...