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dc.contributor.authorArslan, Mikail
dc.contributor.authorTak, Tuğba
dc.contributor.authorErgün, Adem
dc.contributor.authorGencer, Nahit
dc.contributor.authorArslan, Oktay
dc.date.accessioned2019-08-09T06:23:02Z
dc.date.available2019-08-09T06:23:02Z
dc.date.issued2018en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.urihttps://hdl.handle.net/20.500.12462/5954
dc.descriptionArslan, Mikail (Balikesir Author)en_US
dc.description.abstractGST is the most important detoxifying enzyme of environmental pollutants, such as carcinogenic matters, heavy metals, some of drugs and pesticides. In this study, hydrophobic gel having a chemical structure of Sepharose 4B-L-tyrosine naphthylamine (STN), for the first time, was used for the purification of Broiler chicken glutathione S-transferase (bcGST). The effects of pesticides namely, Delmetrin (R), Mamba Turbo (R), Alpgor (R) and Petra (R) on purified bcGST activity were determined. Among the pesticides tested, Delmetrin (R) and Petra (R) had very strong inhibitory effects on bcGST with IC50 values of 28 mu M, 45 mu M, respectively, but the activity of enzyme was poorly inhibited by Mamba Turbo (R). On other hand, Alpgor (R) with dimethoate had no inhibitory effect on bcGST at the working concentration (20-60 mu M).en_US
dc.language.isoengen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlutathione S-transferaseen_US
dc.subjectPesticidesen_US
dc.subjectHydrophobic Interactionen_US
dc.subjectBroilersen_US
dc.titleEffects of four pesticides on broilers glutathione-s-transferase activityen_US
dc.typearticleen_US
dc.relation.journalFresenius Environmental Bulletinen_US
dc.contributor.departmentSusurluk Meslek Yüksekokuluen_US
dc.contributor.authorID0000-0002-7882-9586en_US
dc.contributor.authorID0000-0001-7092-8857en_US
dc.identifier.volume27en_US
dc.identifier.issue12Ben_US
dc.identifier.startpage9529en_US
dc.identifier.endpage9534en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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