The effect of sodium tetraborate on antioxidant enzymes under in vitro conditions
Özet
Herein, the effects of sodium tetraborate on antioxidant enzyme activities from human blood cells under in vitro conditions were studied. Red blood cells were exposed to different concentrations of sodium tetraborate. Biochemical parameters, such as catalase (CAT), superoxide dismutase (SOD), glutathione-S-transferase (GST), glutathione reductase (GSH), glutathione peroxidase (GSH-Px) and glucose-6-phosphate dehydrogenase (G-6-PDH) were examined to determine oxidative stress. According to our findings, boron compounds at low concentrations were useful in supporting antioxidant enzyme activities in human red blood cells. Sodium tetraborate showed the effects of being neither activator nor inhibitor for all enzymes studied. The results of this study led us to conclude that there were no significant effects on antioxidant enzyme activities of the sodium tetraborate in the studied concentration ranges.
