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dc.contributor.authorŞarkış, Cihat
dc.contributor.authorCağlar, Erkan
dc.contributor.authorUğurlu, Serdal
dc.contributor.authorÇetinkaya, Emel
dc.contributor.authorTekin, Nilüfer
dc.contributor.authorArslan, Mübeccel
dc.contributor.authorÖzdemir, Sebati
dc.contributor.authorTuncer, Murat
dc.descriptionŞarkış, Cihat (Balikesir Author)en_US
dc.description.abstractIntroduction Familial Mediterranean fever (FMF) is a periodic febrile disease characterized by acute recurrent episodes of serositis. Liver disease is not considered a part of the spectrum of clinical manifestations of FMF. Objective The purpose of this study was to characterize the nonalcoholic fatty liver disease (NAFLD) that could be associated with familial Mediterranean fever (FMF). Methods Clinical findings and treatment information of the patients with FMF were obtained from outpatient files. Weight, height, hip and waist circumference, blood pressure, blood C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), fibrinogen, glucose, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), creatinine, alanine aminotransferase (ALT), and insulin levels were determined in all subjects, and additionally liver ultrasonography was performed for signs of hepatosteatosis. Results Fifty-two age and gender matched patients with FMF, and 30 healthy controls were included in the study. The prevalence of metabolic syndrome in the patient group was determined to be significantly higher in the patient group compared to the healthy group. When FMF patients with and without hepatosteatosis were compared, the prevalence of metabolic syndrome was determined to be 6 vs. 3, respectively (p<0.001). Eleven patients with FMF were found to have grade 1-2 hepatosteatosis, and only 6 of healthy subjects had grade 1 hepatoseatosis (p=0.901). Conclusion When compared with healthy controls, we found the prevalence of NAFLD was not increased in patients with FMF.en_US
dc.publisherSrpsko Lekarsko Drustvoen_US
dc.subjectFamilial Mediterranean Feveren_US
dc.subjectNonalcoholic Fatty Liver Diseasesen_US
dc.subjectMetabolic Syndromeen_US
dc.titleNonalcoholic fatty liver disease and familial mediterranean fever: Are they related?en_US
dc.relation.journalSrpski Arhiv Za Celokupno Lekarstvoen_US
dc.contributor.departmentTıp Fakültesien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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