Browsing by Author "Şimşek, Hasan"
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The effects of medical ozone on oxidative stress in lung tissue of diabetic rats
Erken, Gülten; Koçak, Fatma Emel; Aslan, Figen; Şimşek, Hasan; Erken, Haydar Ali (Wiley-Blackwell, 2016)AIM: Ozone is a trivalent form of oxygen. Medical ozone is a mixture of ozone and oxygen. Relationship between oxidant stress and diabetic complications has been shown previously. In thisstudy, it was aimed to investigate ... -
Nephrotoxic effects of varenicline as the most effective drug used for smoking cessation: A preliminary experimental study
Koç, Akif; Erken, Haydar Ali; Koçak, Fatma Emel; Yay, Arzu; Güçlü, Aydin; Sarı, Erhan; Şimşek, Hasan; Önder, Gözde Özge (Springer, 2015)Varenicline is a new most effective drug for smoking cessation. Its effect on kidney functions remains unclear. This study purposed to investigate whether varenicline causes nephrotoxicity in rats. Fifteen rats were randomly ... -
Single dose varenicline may trigger epileptic activity
Erken, Haydar Ali; Erken, Gülten; Şimşek, Hasan; Korkut, Oğuzhan; Koç, Emine Rabia; Yavuz, Özlem; Genç, Osman (Springer-Verlag Italia Srl, 2014)Varenicline is a new drug for smoking cessation, and its effect on epilepsy is not clear. The aim of this study was to investigate whether different doses of varenicline cause epileptic activity. Forty rats were randomly ... -
What are the mechanisms mediating the neuroprotective effects of ozone in diabetic neuropathy?
Erken, Haydar Ali; Erken, Gülten; Akcılar, Raziye; Koçak, Fatma Emel; Yay, Arzu Hanım; Şimşek, Hasan; Önder, Gözde Özge; Akcılar, Aydın (Wiley-Blackwell, 2016)AIM: Ozone, which hastherapeutic effect in many pathologies, partially prevented diabetic neuropathy in ratsin our previousstudy. In the present study, it was investigated that the mechanisms mediating the neuroprotective ...