Browsing by Author "Atahan, Alparslan"
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Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors
Sönmez, Fatih; Sevmezler, Sedat; Atahan, Alparslan; Ceylan, Mustafa; Demir, Dudu; Gençer, Nahit; Arslan, Oktay; Küçükislamoğlu, Mustafa (Pergamon-Elsevier Science Ltd, 2011)A newly series of 4-(phenylurenyl) chalcone (4a-j) and 4'-(phenylurenyl/thiourenyl)chalcone (9a-l) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. ... -
In vitro inhibition effect of some chalcones on erythrocyte carbonic anhydrase i and II
Gençer, Nahit; Bilen, Çiğdem; Demir, Dudu; Atahan, Alparslan; Ceylan, Mustafa; Küçükislamoğlu, Mustafa (Informa Healthcare, 2013)In this study, 4'-(phenylurenyl/thiourenyl) chalcones (14-25) were prepared from 4'-(phenylurenyl/thiourenyl)acetophenones and benzaldehyde derivatives by Claisen-Schmidt condensation. In vitro inhibition effects of chalcone ... -
Synthesis, biological activity and structure-activity relationship of novel diphenylurea derivatives containing tetrahydroquinoline as carbonic anhydrase I and II inhibitors
Atahan, Alparslan; Gencer, Nahit; Bilen, Çiğdem; Yavuz, Emre; Genç, Hayriye; Sönmez, Fatih; Zengin, Mustafa; Ceylan, Mustafa (Wiley-V C H Verlag GMBH, 2018)A series of novel tetrahydroquinoline derivatives containing urea moiety was synthesized and their invitro inhibitory effects on the human carbonic anhydrase isoenzymes (hCA-I and hCA-II) were evaluated by using the CO2 ... -
Synthesis, enzyme inhibition, and molecular docking studies of a novel chalcone series bearing benzothiazole scaffold
Musatat, Ahmad Badreddin; Atahan, Alparslan; Ergün, Adem; Çıkrıkcı, Kübra; Gençer, Nahit; Arslan, Oktay; Zengin, Mustafa (Wiley, 2023)This study reports the facile synthesis of a novel series of benzothiazole-chalcones, in addition to their inhibitory profile on important metabolic enzymes including human carbonic anhydrases (hCA-I, hCA-II) and paraoxonase ...
