Browsing by Author "Aydemir, Tuğşen"

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Evaluation of the effects of dexketoprofen trometamol on knee joint: An in vivo & in vitro study

Sağır, Özlem; Sunay, Fatma Bahar; Yıldırım, Hatice; Aksöz, Elif; Özaslan, Sabri; Köroğlu, Ahmet; Aydemir, Tuğşen; Ulusal, Ali Engin; Köçkar, Feray (Indian Council Medical RES, 2013)

Background & objectives: Intra-articular (ia) injections of local anaesthetics and non-steroidal anti-inflammatory drugs (NSAID's) are simple and efficient to ensure post-operative analgesia but some of these have toxic ...
Induction of human ADAMTS-2 gene expression by IL-1 alpha is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells

Alper, Meltem; Aydemir, Tuğşen; Köçkar, Feray (Elsevier Science BV, 2015)

Up-regulation of ADAMTS genes with proinflammatory cytokines is important for some pathological conditions such as osteoarthritis (OA) that is a disease based on ECM degradation in cartilage. IL-1 alpha is a proinflammatory ...