Browsing by Author "Berber, Nurcan"
Now showing items 1-4 of 4
-
Synthesis and evaluation of new phthalazine substituted beta-lactam derivatives as carbonic anhydrase inhibitors
Berber, Nurcan; Arslan, Mustafa; Bilen, Çiğdem; Saçkes, Zübeyde; Gencer, Nahit; Arslan, Oktay (Maik Nauka / Interperiodica / Springer, 2015)A new series of phthalazine substituted beta-lactam derivatives were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA I and II) were evaluated. 2H-Indazolo[2,1-b]phthalazine-trione ... -
Synthesis and evaluation of new phthalazine urea and thiourea derivatives as carbonic anhydrase inhibitors
Berber, Nurcan; Arslan, Mustafa; Yavuz, Emre; Bilen, Ciğdem; Gençer, Nahit (Hindawi Publishing Corp, 2013)A new series of phthalazine substituted urea and thiourea derivatives were synthesized, and their inhibitory effects on the activity of purified human carbonic anhydrases (hCAs I and II) were evaluated. 2H-Indazolo[2,1-b ... -
Synthesis of new series of thiazol-(2(3H)-ylideneamino)benzenesulfonamide derivatives as carbonic anhydrase inhibitors
Berber, Nurcan; Arslan, Mustafa; Vural, Fırat; Ergun, Adem; Gencer, Nahit; Arslan, Oktay (Wiley, 2020)Human carbonic anhydrase I and II isoenzymes (hCA I and II) are important metabolic enzymes. In this study, a new series of thiazol-(2(3H)-ylideneamino)benzenesulfonamide derivatives were synthesized and also some inhibition ... -
Synthesis, characterization, carbonic anhydrase inhibitor activity, and docking studies of phenylthiazol-2(3h)-ylidene-isoquinoline-5-amine derivatives
Berber, Nurcan; Şahutoğlu, Arif Sercan; Gökçe, Başak; Çıkrıkçı, Kübra; Gençer, Nahit (Elsevier, 2023)Phenylthiazol-2(3h)-ylidene-isoquinoline-5-amine derivatives(5a-r) were easily prepared from 5-aminoisoquinoline, thioisocyanate, and phenacyl bromide derivatives in the presence of triethylamine in tetrahydrofuran (THF), ...