Browsing by Author "Bilen, Ciğdem"
Now showing items 1-4 of 4
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The effects of ex vivo ozone treatment on human erythrocyte carbonic anhydrase enzyme
Erken, Gülten; Erken, Haydar Ali; Bilen, Ciğdem; Gencer, Nahit (Taylor & Francis Ltd, 2018)Ozone autohemotherapy is used in the treatment of some diseases. Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes and play a role in homeostatic mechanisms. The aim of this study was to investigate the effects of ... -
Is the COPD assessment test (CAT) effective in demonstrating the systemic inflammation and other components in COPD?
Sarıoğlu, Nurhan; Hişmioğulları, Adnan Adil; Bilen, Ciğdem; Erel, Fuat (Elsevier Espana Slu, 2016)Introduction: Chronic obstructive pulmonary disease (COPD) is currently a complex, multicomponent disorder. The COPD Assessment Test (CAT) has been increasingly used to assess COPD patients. This study aims to investigate ... -
Synthesis and evaluation of new phthalazine urea and thiourea derivatives as carbonic anhydrase inhibitors
Berber, Nurcan; Arslan, Mustafa; Yavuz, Emre; Bilen, Ciğdem; Gençer, Nahit (Hindawi Publishing Corp, 2013)A new series of phthalazine substituted urea and thiourea derivatives were synthesized, and their inhibitory effects on the activity of purified human carbonic anhydrases (hCAs I and II) were evaluated. 2H-Indazolo[2,1-b ... -
Synthesis and evaluation of sulfonamide-bearing thiazole as carbonic anhydrase isoforms hCA I and hCA II
Kılıçaslan, Soner; Arslan, Mustafa; Rüya, Zeynep; Bilen, Ciğdem; Ergün, Adem; Gençer, Nahit; Arslan, Oktay (Taylor & Francis Inc, 2016)Sulfonamide-bearing thiazole compounds were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase I and II were evaluated. Human carbonic anhydrase isoenzymes (hCA-I and hCA-II) were ...
