Browsing by Author "Canpolat, Sinan"
Now showing items 1-7 of 7
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Asprosin, a novel glucogenic adipokine: a potential therapeutic implication in diabetes mellitus
Hekim, Münevver Gizem; Kelestemur, Muhammed Miraç; Bulmuş, Funda Gülcü; Bilgin, Batuhan; Bulut, Ferah; Gökdere, Ebru; Özdede, Mehmet Rıdvan; Kelestimur, Haluk; Canpolat, Sinan; Özcan, Mete (Taylor & Francis Ltd, 2021)Objectives: We aimed to investigate the effects of asprosin on diabetes with a focus on serum glucose, irisin, ghrelin, leptin levels and hepatic levels of triglycerides (TG), cholesterol, low-density lipoprotein ... -
Asprosin, a novel therapeutic candidate for painful neuropathy: An experimental study in mice
Özcan, Sibel; Kelestemur, Muhammed Miraç; Hekim, Müğnevver Gizem; Bulmuş, Özgür; Bulut, Ferah; Bilgin, Batuhan; Canpolat, Sinan (Springer, 2022)Recent studies indicate presence of a strong link between adipokines and neuropathic pain. However, the effects of asprosin, a novel adipokine, on neuropathic pain have not been studied in animal models. Mouse models were ... -
The effects of irisin hormone on seminal vesicle fluid in male rats administered paroxetine
Bulmuş, Özgür; Bulmuş, Funda Gülcü; Serhatlıoğlu, İhsan; Canpolat, Sinan (Wiley, 2023)It is known that antidepressants cause some negative effects in the reproductive system and especially in sperm parameters. It is stated that exercise is an effective factor on the transition to puberty, reproductive ... -
Effects of treadmill exercise on sexual behavior and reproductive parameters in chronically stressed-male rats
Kelestimur, Haluk; Bulmuş, Özgür; Serhatlıoğlu, İhsan; Ercan, Zübeyde; Kaya, Şeyma Özer; Yardımcı, Ahmet; Ülker, Nazife; Kaçar, Emine; Canpolat, Sinan (Acad Sciences Czech Republic, 2021)Exposure to chronic stress stimulates the hypothalamic-pituitary adrenal (HPA) axis and then simultaneously inhibits hypothalamic-pituitary-gonadal axis (HPG) axis activity. The inhibition formed by the HPA axis is the ... -
Evaluation of the effects of systemic irisin application on guided bone regeneration in peri-implant bone defects
Bulmuş, Özgür; Dündar, Serkan; Bozoğlan, Alihan; Artas, Gökhan; Kirtay, Mustafa; Canpolat, Sinan (Lippincott Williams & Wilkins, 2022)This study aimed to investigate the effects of systemic irisin hormone application on new bone formation in periimplant bone defects. After surgically creating peri-implant bone defects in the metaphyseal part of the ... -
Evaluation of the effects of systemic irisin hormone application on osseointegration of titanium implants: An experimental study
Bulmuş, Özgür; Dündar, Serkan; Bozoğlan, Alihan; Canpolat, Sinan (Lippincott Williams & Wilkins, 2022)This study aimed to conduct a biomechanical investigation of the effects of systemic irisin hormone application on the osseointegration of titanium implants in rat tibias. After surgical implementation of titanium implants ... -
Irisin ameliorates male sexual dysfunction in paroxetine-treated male rats
Canpolat, Sinan; Ülker, Nazife; Yardımcı, Ahmet; Tancan, Emre; Şahin, Elif; Yaman, Serap Özer; Bulmuş, Özgür; Alver, Ahmet; Özcan, Mete (Pergamon-Elsevier Science Ltd, 2021)Sexual dysfunction is a common clinical condition due to different causes including the use of selective serotonin reuptake inhibitors (SSRI). Especially, SSRI paroxetine is known to cause numerous types of sexual dysfunction ...
