Browsing by Author "Ceylan, Mustafa"
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Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors
Sönmez, Fatih; Sevmezler, Sedat; Atahan, Alparslan; Ceylan, Mustafa; Demir, Dudu; Gençer, Nahit; Arslan, Oktay; Küçükislamoğlu, Mustafa (Pergamon-Elsevier Science Ltd, 2011)A newly series of 4-(phenylurenyl) chalcone (4a-j) and 4'-(phenylurenyl/thiourenyl)chalcone (9a-l) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. ... -
In vitro inhibition effect of some chalcones on erythrocyte carbonic anhydrase i and II
Gençer, Nahit; Bilen, Çiğdem; Demir, Dudu; Atahan, Alparslan; Ceylan, Mustafa; Küçükislamoğlu, Mustafa (Informa Healthcare, 2013)In this study, 4'-(phenylurenyl/thiourenyl) chalcones (14-25) were prepared from 4'-(phenylurenyl/thiourenyl)acetophenones and benzaldehyde derivatives by Claisen-Schmidt condensation. In vitro inhibition effects of chalcone ... -
Synthesis of thiosemicarbazones as substrates for xanthine oxidase enzyme activity
Beyaztaş, Serap; Fındık, Esra; Ceylan, Mustafa; Arslan, Oktay (Chemical Publishing Co., 2014)Thiosemicarbazones were synthesized from 7-arylbicyclo[3.2.0]hept-2-en-6-ones (1a-d) and thiosemicarbazide. The compounds were purified on a silica gel column chromatography. The thiosemicarbazone compounds were tested in ... -
Synthesis, biological activity and structure-activity relationship of novel diphenylurea derivatives containing tetrahydroquinoline as carbonic anhydrase I and II inhibitors
Atahan, Alparslan; Gencer, Nahit; Bilen, Çiğdem; Yavuz, Emre; Genç, Hayriye; Sönmez, Fatih; Zengin, Mustafa; Ceylan, Mustafa (Wiley-V C H Verlag GMBH, 2018)A series of novel tetrahydroquinoline derivatives containing urea moiety was synthesized and their invitro inhibitory effects on the human carbonic anhydrase isoenzymes (hCA-I and hCA-II) were evaluated by using the CO2 ...