Browsing by Author "Demirtaş, Selim"

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The efficacy of tyrosine kinase inhibitor dasatinib on colonic mucosal damage in murine model of colitis

Can, Günay; Ayvaz, Süleyman; Can, Hatice; Karaboğa, İhsan; Demirtaş, Selim; Aksit, Hasan; Yılmaz, Begümhan; Korkmaz, Mustafa; Kurt, Mevlüt; Karaca,Turan (Oxford Univ, 2016)

Background: Ulcerative colitis is an inflammatory condition limited to the colon in the gastrointestinal system. Currently the most potent medications used for medical treatment of ulcerative colitis produce no response ...
The syk inhibitor fostamatinib decreases the severity of colonic mucosal damage in a rodent model of colitis

Can, Güray; Ayvaz, Süleyman; Can, Hatice; Demirtaş, Selim; Akşit, Hasan; Yılmaz, Bülent; Korkmaz, Uğur; Kurt, Mevlüt; Karaca, Turan (Oxford Univ Press, 2015)

Background and aims: Inflammatory bowel disease is a chronic inflammatory disease of the gastrointestinal system. In some cases, current medications used for inflammatory bowel disease may not be enough for remission, ...