Browsing by Author "Eser, Betül"
Now showing items 1-15 of 15
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The analyses of C677T and A1298C polymorphisms on the MTHFR gene and factor V Leiden mutation in pseudotumor cerebri patients
Coşar, Murat; Eser, Betül; Erdoğan, Müjgan Özdemir; Eser, Olcay; Aslan, Adem; Yıldız, Handan; Korkmaz, Serhat; Yavaş, Güliz Fatma (Gene Therapy Press, 2013)Background: In this study, we aimed to investigate the genetic factors which may cause to thrombosis such as C677T and A1298C methylen-thetrahydropholate reductase (MTHFR) gene polymorphisms and Factor V Leiden ... -
Dejeneratif disk hastalığı ve genetik
Eser, Betül; Sönmez, Mehmet Akif; Eser, Olcay (2013)Dejeneratif disk hastalığı (DDH) en sık rastlanan omurga hastalıklarından biridir. Etyolojisi tam olarak bilinmemesine rağmen son yıllarda yapılan çalışmalar bu hastalığın genetik ve çevresel faktörlerin etkileşimiyle ... -
A deletion mutation of the connexin 26 (Gjb2) gene in a Turkish patient with vohwinkel syndrome
Öztürk, Savaş; Can, İlkay; Eser, Betül; Yazıcı, Hasan (Medecine Et Hygiene, 2016)A deletion mutation of the connexin 26 (gjb2) gene in a Turkish patient with Vohwinkel syndrome: Vohwinkel syndrome (VS), also known as keratoderma hereditaria mutilans, is a rare keratinization genetic disorder characterized ... -
The effects of IL-1A and IL-6 genes polymorphisms on gene expressions, hormonal and biochemical parameters in polycystic ovary syndrome
Eser, Betül; Taşkın, Mine İslimye; Hişmioğulları, Adnan Adil; Akşit, Hasan; Bodur, Abdurrahman Said (Taylor and Francis Ltd, 2017)Polycystic ovary syndrome (PCOS) is a multifactorial disease characterised by chronic inflammation. We aimed to investigate an association between IL-1A and IL-6 gene polymorphisms and both hormonal/biochemical parameters ... -
Effects of MMP-1 and MMP-3 gene polymorphisms on gene expression and protein level in lumbar disc herniation
Eser, Betül; Eser, Olcay; Yüksel, Yasin; Akşit, Hasan; Karavelioğlu, Ergün; Tosun, Murat; Şekerci, Zeynep (Funpec-Editora, 2016)The aim of this study was to identify the possible correlation between polymorphisms in matrix metalloproteinase (MMP)-1 and MMP-3 and their corresponding protein levels in disc tissues obtained from patients with lumbar ... -
The effects of polymorphisms of death pathway genes and mitochondrial pathway genes in intervertebral disc degeneration
Eser, Betül; Eser, Olcay; Aslan, Esra; Dolgun, Habibullah (Turkish Neurosurgical Soc, 2017)"AIM: It has been proposed that apoptosis is effective on intervertebral disc degeneration. This study is the first study in which both polymorphisms and expressions of apoptotic genes in patients with intervertebral disc ... -
Evaluation of tool-like receptor-2 and 4 and interleukin-6 gene expressions in Turkish rheumatoid arthritis patients
Eser, Betül; Şahin, Nilay (Springer London Ltd, 2016)Rheumatoid arthritis (RA) is a progressive inflammatory disease. Although the etiology and pathogenesis of RA are not known well, genetic and environmental factors are proposed to initiate an autoimmune process. We aimed ... -
Increased expression of matrix metalloproteinases in ligamentum flavum hypertrophy of the patients with lumbar spinal stenosis
Eser, Betül; Eser, Olcay; Şimşek, Nejdet; Bülbül, Erdoğan; Güven, Mustafa (Kamla-Raj Enterprises, 2016)This paper shows an investigation of the expressions of MMP-3,-13 and their polymorphisms in patients with lumbar spinal stenosis (LSS). Hypertrophied LF tissues and peripheral bloods were obtained from 50 patients with ... -
Lack of association between the methylenetetrahydropholate reductase gene A1298C polymorphism and neural tube defects in a Turkish study group
Yıldız, Saliha Handan; Erdoğan, Müjgan Özdemir; Solak, Mustafa; Eser, Olcay; Terzi, Evrim Suna Arıkan; Eser, Betül; Kocabaş, Volkan; Aslan, Adem (Funpec-Editora, 2016)The etiology underlying neural tube defects (NTDs) is not fully understood and is believed to involve a complex milieu of genetic and environmental factors. The A1298C polymorphism in the methylenetetrahydropholate reductase ... -
Mineralocorticoid receptor gene-2G/C polymorphism in central serous chorioretinopathy and relation of polymorphism with plasma cortisol levels
Yazıcı, Alper; Sarı, Esín Söǧütlü; Eser, Betül; Şahin, Gözde; Alpdemir, Medine; Kılıç, Adil; Erol, Muhammed Kazım; Ermiş, Sıtkı Samet (International Journal of Ophthalmology (c/o Editorial Office), 2016)AIM: To evaluate the mineralocorticoid receptor (MR) gene-2G/C single nucleotide polymorphism in central serous chorioretinopathy (CSCR), polymorphism and plasma cortisol level relationship. METHODS: Sixty CSCR patients ... -
NUCB2 gene polymorphism and its relationship with nesfatin-1 levels in polycystic ovary syndrome
Taşkın, Mine İslimye; Eser, Betül; Adalı, Ertan; Kara, Hayrettin; Cüce, Coşkun; Hişmioğulları, Adnan Adil (Taylor & Francis Ltd, 2016)Nesfatin-1, encoded by the nucleobindin-2 (NUCB2) gene, is an anorexigenic protein related to energy metabolism, obesity, and insulin resistance. The aim of this study was to evaluate NUCB2 gene polymorphism (rs757081) and ... -
Prenatal diagnosis of a de novo partial trisomy 17q case associated with increased nuchal translucency, hypoplastic left heart syndrome, cerebral anomalies: Case report
Türe, Mehmet; Saǧ, Şebnem Özemri; Gülten, Emine Tuna; Eser, Betül; Şahintürk, Serdar; Demir, Bilge Çetinkaya; Yakut, Tahsin (Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2016)Partial trisomy of distal 17q is rare. Until now, 32 cases of partial trisomy for the distal region of 17q were reported. Our case has multiple anomalies, such as increased nuchal translucency, hypoplastic left heart ... -
The prevalence of 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene in central serous chorioretinopathy and its association with plasma PAI-1 levels
Sarı, Esin Sögütlü; Yazıcı, Alper; Eser, Betül; Erol, Muhammet Kazım; Kılıç, Adil; Ermiş, Sıtkı Samet; Koytak, Arif; Aksit, Hasan (Informa Healthcare, 2014)Context: Central serous chorioretinopathy (CSCR) is a poorly understood disease and the choroidal circulation abnormality induced by the plasminogen activator inhibitor type 1 (PAI-1) seems to be associated with the ... -
Two different mutations of gli3 gene in two different syndromes
Candan, Şükrü; Yeşil, Gözde; Şen, Eylem Dalkıran; Eser, Betül (Medecine Et Hygiene, 2016)Two different mutations of GLI3 gene in two different syndromes: Polydactyly is among common extremity abnormalities. Mutations of GLI3 gene have been reported commonly in Greig Cephalopolysyndactyly Syndrome (GCPS) and ... -
Two different nucleotide substitutions of APC gene in a family with familial adenomatous polyposis
Eser, Betül; Yıldar, Murat (Oxford Univ Press, 2015)Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome leading to colorectal cancer. This disease appears as a result of germline mutation in adenomatous polyposis coli (APC) gene. The aim of the present ...
