Browsing by Author "Gökbulut, Cengiz"
Now showing items 1-20 of 26
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An alternative treatment method for poisoning in veterinary medicine: Intravenous lipid emulsion
Akyol, Büşra Aslan; Gökbulut, Cengiz (Animal Health, Production and Hygiene, 2021)Animal poison control centers receive numerous complaints about possible ingestion of substances that can cause deadly toxicities in the home. In recent years, over-the-counter medications such as ibuprofen, acetaminophen, ... -
Anthelmintic drugs used in equine species
Gökbulut, Cengiz; McKellar, Quintin A. (Elsevier Science, 2018)Internal parasites of horses comprise an intractable problem conferring disease, production and performance losses. Parasitism can rarely be controlled in grazing horses by management alone and anthelmintic drugs have ... -
Breed-related plasma disposition and faecal excretion of eprinomectin after subcutaneous administration in sheep
Kütahya, Zeynep Özdemir; Akyol, Büşra Aslan; Deliklitaş, Kübra; Gökbulut, Cengiz (Elsevier B.V., 2023)Eprinomectin is a member of the avermectin family, exhibiting a broad-spectrum activity as well as a minimal elimination by milk in lactating animals. It is known that pharmacokinetic parameters are fundamental to the ... -
Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats
Akşit, Dilek; Yalınkılıç, Hande Sultan; Sekkin, Selim; Boyacıoğlu, Murat; Çırak, Veli Yilgor; Ayaz, Erol; Gökbulut, Cengiz (BMC, 2015)Background: The aims of this study were to compare the pharmacokinetics of albendazole sulfoxide (ABZ-SO, ricobendazole) in goats and sheep at a dose of 5 mg/kg bodyweight (BW), after intravenous (IV) and subcutaneous (SC) ... -
Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration
Gökbulut, Cengiz; Yalınkılınç, Hande Sultan; Akşit, Dilek; Veneziano, Vincenzo (Canadian Vet Med Assoc, 2014)Since there is no registered anthelmintic drug available for use in goats, extra-label use of drugs is a common practice in most countries. The aim of the present study was to compare the pharmacokinetic disposition of ... -
Comparative plasma and milk dispositions,faecal excretion and efficacy of per os ivermectin and pour-on eprinomectin in horses
Gökbulut, Cengiz; Özüiçli, Mehmet; Akşit, Dilek; Aksöz, Elif; Korkut, Oǧuzhan; Yalçınkaya, M.; Çırak, Veli Yılgör (Wiley-Blackwell, 2016)The horse milk gains increasing interest as a food product for sensitive consumers, such as children with food allergies or elderly people. We investigated the plasma and milk disposition, faecal excretion and efficacy of ... -
Comparative plasma dispositions of meloxicam and carprofen following oral administration in dogs
Karademir, Ümit; Gökbulut, Cengiz; Akar, Ferda (Univ Fed Rio Grande Do Sul, 2015)Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are used extensively in several domestic animal species for the treatment of a range of musculo-skeletal disorders and soft tissue injuries or inflammatory conditions. ... -
Determination of the differences in penetration of tigecycline and vancomycin ınto bronchial epithelium of normal and cystic fibrosis lung
Günay, Necati; Akar, Ferda; Gökbulut, Cengiz; Sakarya, Serhan (AVES, 2018)Objective: We aimed to investigate the dose and time course of tigecycline and vancomycin for effective intracellular concentration in bronchial epithelium of normal and cystic fibrosis lung. Methods: Differences between ... -
The effect of fasting on the plasma disposition of albendazole in goats
Karademir, Ümit; Gökbulut, Cengiz; Boyacıoğlu, Murat (Kafkas Univ, 2015)This study was designed to investigate the effect of fasting on the plasma disposition of albendazole (ABZ) in goats following oral administration. A total of 10 goats, aged 5-6 months were used in this study. The animals ... -
The effect of intravenous lipid emulsion (ILE) on the pharmacokinetic/toxicokinetic dispositions of ivermectin and carprofen in rabbits
Akyol, Buşra Aslan; Gökbulut, Cengiz (Springer, 2023)Intravenous lipid emulsion (ILE) has been widely used as an effective antidote in both veterinary and human medicine for the treatment of acute intoxications caused by drugs and pesticides with high lipid solubility. This ... -
The effect of surgery (Ovariohysterectomy) on the plasma disposition of meloxicam following intravenous administration in dogs
Karademir, Ümit; Akşit, Dilek; Kum, Cavit; Erdogan, Hasan; Uçar, Eyüp Hakan; Peker, Cevdet; Gökbulut, Cengiz (BMC, 2016)Background: Meloxicam (MLX) is a nonsteroidal anti-inflammatory drug used in the relief of postoperative pain for human and veterinary medicine. This study was designed to investigate the effect of surgery on the plasma ... -
Evaluation of the anthelmintic activity of pumpkin seeds (Cucurbita maxima) in mice naturally infected with aspiculuris tetraptera
Ayaz, Erol; Gökbulut, Cengiz; Coşkun, Hamit; Uçar Türker, Arzu; Özsoy, Şeyda; Ceylan, Kübra (Academic Journals Inc., 2015)The aim of this study was to investigate the anthelmintic effect of pumpkin seeds (Cucurbita maxima) against Aspiculuris tetraptera in naturally infected mice. For this purpose, the natural infection was determined by the ... -
The impact of nano/micro-plastics toxicity on seafood quality and human health: Facts and gaps
Gündoğdu, Sedat; Rathod, Nikheel; Hassoun, Abdo; Jamroz, Ewelina; Kulawik, Piotr; Gökbulut, Cengiz; Ait-Kaddour, Abderrahmane; Özoğul, Fatih (Taylor & Francis Inc, 2022)Contamination of the food and especially marine environment with nano/micro-plastic particles has raised serious concern in recent years. Environmental pollution and the resulting seafood contamination with microplastic ... -
In vitro efficacy of alphacypermethrin on the buffalo louse Haematopinus tuberculatus (Burmeister, 1839)
Veneziano, Vincenzo; Neglia, Gianluca; Buono, Francesco; Pacifico, Laura; Manna, Laura; Santoro, Mario; Gökbulut, Cengiz (Kasetsart University, 2017)In Italy buffalo farms adopted intensive breeding techniques, however the high density of animals in intensive breeding favours the diffusion of ectoparasites, such as louse. The aim of this study was to determine the in ... -
In vivo exposure of Albendazole sulphoxide by Haemonchus contortus and correlation between plasma and target tissue or gastrointestinal content dispositions in goats
Gökbulut, Cengiz; Çırak, Veli Y.; Aypak, Suleyman; Avcı, Hamdi; Sekkin, Selim; Yalınkılınç, Hande S.; Boğa, Buket; Ayaz, Erol (Wiley, 2021)Sheep and goats are sharing different helminth parasites including Haemonchus contortus. Control of these helminths is based mainly on the use of anthelmintics. However, in goats, the application of anthelmintics is often ... -
Plasma disposition and faecal excretion of eprinomectin following subcutaneous administration in Saanen and Alpine goats
Kütahya, Zeynep Özdemir; Akyol, Büşra Aslan; Deliklitaş, Kübra; Gökbulut, Cengiz (Elsevier B.V., 2023)Eprinomectin is extensively used in veterinary medicine, particularly in the treatment of internal and external parasites in livestock, including goats. The pharmacokinetic behavior of eprinomectin in plasma and faeces was ... -
Plasma disposition and faecal excretion of eprinomectin following topical and subcutaneous administration in non-lactating dairy cattle
Akşit, Dilek; Korkut, Oğuzhan; Aksöz, Elif; Gökbulut, Cengiz (Taylor & Francis Inc, 2016)AIMS: To investigate the plasma disposition and faecal excretion of eprinomectin (EPM) in non-lactating dairy cattle following topical and S/C administration.METHODS: Holstein dairy cows, 3.5-5 years-old, were selected ... -
Plasma disposition, milk excretion and parasitological efficacy of mebendazole in donkeys naturally infected by Cyathostominae
Gökbulut, Cengiz; Akşit, Dilek; Santoro, Mario; Roncoroni, Cristina; Mariani, Ugo; Buono, Francesco; Rufrano, Domenico; Veneziano, Vincenzo; Fagiolo, Antonio; 0000-0002-8487-1051 (Elsevier Sci Ltd, 2016)Mebendazole (MBZ) has been licensed for use in horses and donkeys, however there are no data available in the literature regarding its pharmacokinetic disposition and efficacy in donkeys. This study was designed to determine ... -
Plasma dispositions and concentrations of ivermectin in eggs following treatment of laying hens
Çırak, Veli Yılgör; Akşit, Dilek; Cihan, Hüseyin; Gökbulut, Cengiz (Taylor & Francis Ltd, 2018)AIMS: To determine the plasma disposition and concentrations of ivermectin (IVM) in eggs produced by laying hens following S/C, oral and I/V administration.METHODS: Twenty-four laying hens, aged 37 weeks and weighing 1.73 ... -
Plasma pharmacokinetics, faecal excretion and efficacy of pyrantel pamoate paste and granule formulations following per os administration in donkeys naturally infected with intestinal strongylidae
Gökbulut, Cengiz; Akşit, Dilek; Smaldone, Giorgio; Mariani, Ugo; Veneziano, Vincenzo (Elsevier Science Bv, 2014)The plasma disposition, faecal excretion and efficacy of two formulations of pyrantel pamoate in donkeys were examined in a controlled trial. Three groups of seven donkeys received either no medication (control) or pyrantel ...
