Browsing by Author "Günaldı, Ömür"
Now showing items 1-9 of 9
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AGR2 gene expression in glioblastoma: A novel molecular potential target for diagnosis and treatment
Adilay, Hüseyin Utku; Evran, Şevket; Katar, Salim; Özdemir, Ahmet; Kayhan, Ahmet; Avcıkurt, Ayla Solmaz; Günaldı, Ömür; Güçlü, Bülent; Tanrıverdi, Osman (Turkish Neurosurgical Society, 2023)AIM: To assess anterior gradient protein 2 (AGR2) gene expression in patients with human glioblastoma (GBM) in comparison to levels in healthy brain tissues. MATERIAL and METHODS: We evaluated the expression levels of AGR2 ... -
Discoidin domain receptor 1 as a promising biomarker for high-grade gliomas
Erdem, Dilek; Günaldi, Meral; Karaman, İrem; Yılmaz, İlhan Ümit; Eseoğlu, Metehan; Avcıkurt, Ayla; Işıksaçan, Nilgün; Erdoğan, Uzay; Günaldı, Ömür (Wolters Kluwer Medknow Publications, 2023)Background: Two fundamental challenges in the current therapeutic approach for central nervous system tumors are the tumor heterogeneity and the absence of specific treatments and biomarkers that selectively target the ... -
Effect of cetuximab on the development of epidural fibrosis based on CD105 and osteopontin ımmunohistochemical staining
Tanrıverdi, Osman; Yılmaz, İhsan; Adilay, Hüseyin Utku; Günaldı, Ömür; Erdoğan, Uzay; Güngör, Abuzer; Kılıç, Mustafa; Tanık, Canan (Lippincott Williams & Wilkins, 2019)Study Design. The effect of cetuximab on the development of epidural fibrosis (EF) was assessed using immunohistochemical methods as well as antibodies for CD105 and osteopontin (OPN). Objective. The goal of this study was ... -
Evaluation of bevacizumab for the treatment of epidural fibrosis by immunohistochemical staining for CD105 and osteopontin
Yılmaz, İlhan; Erdoğan, Uzay; Tanrıverdi, Osman; Günaldı, Ömür; Adilay, Hüseyin Utku; Ömeroğlu, Muhammed; Tanık, Canan; Tuğcu, Bekir (Turkish Neurosurgical Society, 2018)AIM: To evaluate bevacizumab for epidural fibrosis (EF) treatment in an experimental rat model using histopathology as well as immunohistochemical staining for CD105 and osteopontin (OPN). MATERIAL and METHODS: Sixteen ... -
Impact of sorafenib on epidural fibrosis: An immunohistochemical study
Tanrıverdi, Osman; Erdoğan, Uzay; Tanık, Canan; Yılmaz, İlhan; Günaldı, Ömür; Adilay, Hüseyin Utku; Arslanhan, Ayça; Eseoğlu, Metehan (Baishideng Publishing Group Inc., 2018)AIM To determine if sorafenib, an antineoplastic agent, could prevent the development of spinal epidural fibrosis (EF). METHODS The study used CD105 and osteopontin antibodies in an immunohistochemical approach to quantify ... -
Inadvertent Error: Evaluation of Bevacizumab for the Treatment of Epidural Fibrosis by Immunohistochemical Staining for CD105 and Osteopontin
Yılmaz, İIhan; Erdogan, Uzay; Tanrıverdi, Osman; Günaldı, Ömür; Adilay, Hüseyin Utku; Ömeroğlu, Muhammed; Tanık, Canan; Tuğcu, Bekir (Turkish Neurosurgical Soc, 2021)As the authors of the paper titled “Evaluation of Bevacizumab for the Treatment of Epidural Fibrosis by Immunohistochemical Staining for CD105 and Osteopontin” published in 2018, Volume 28(6), pp. 954–962, -
Morphometric analysis of the effects of manuka honey on vasospastic femoral arteries in rats: an experimental study
Tanrıverdi, Osman; Yılmaz, İlhan; Erdoğan, Uzay; Günaldı, Ömür; Güngör, Abuzer; Adilay, Hüseyin Utku; Arslanhan, Ayça; Tuğcu, Bekir (Yerküre Tanitim Yayincilik Hizmetleri As, 2018)Objectives: The aim of this study was to determine if Manuka honey, a potent anti-inflammatory and antioxidant agent, had any effect on the development of vasospasm in an experimental subarachnoidal hemorrhage model ... -
Role of AGR2 expression in specimens from pituitary adenoma tissue on tumor behavior
Doğanşen, Sema Çiftçi; Günaldı, Ömür; Avcıkurt, Ayla Solmaz; Çolluoğlu, Barış; Yılmaz, İlhan (Turkiye Klinikleri, 2020)Objective: To investigate the anterior gradient 2 (AGR2) mRNA expression, which performs various cellular functions such as cell migration, differentiation, and proliferation in tissue specimens from pituitary adenomas. ... -
Ubiquitin-specific protease 8 gene expression in sporadic pituitary adenomas
Hatipoğlu, Esra; Günaldı, Ömür; Erkan, Buruç; Avcıkurt, Ayla Solmaz; Mert, Meral; Niyazoğlu, Mutlu (Maghira & Maas Publications, 2022)OBJECTIVES: In sporadic pituitary adenomas, the role of Ubiquitin-specific protease 8 (USP8) is not clearly defined. Mutations in USP8 gene are known to influence formation of the corticotroph adenomas. However, it has not ...
