Browsing by Author "Kaya, Mustafa Oğuzhan"
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Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase
Kaya, Mustafa Oğuzhan; Kaya, Yeşim; Gül, Gülşah Çelik; Kurtuluş, Figen; Arslan, Oktay; Güler, Özen Özensoy (Informa Healthcare, 2015)In this preliminary study, a new series of some cerium vanadate derivatives have been investigated as new type of inhibitors of xanthine oxidase (XO; E.C 1.17.3.2). XO is a superoxide-producing enzyme found normally in ... -
An examination of hyaluronidase enzyme activity in four different sheep breeds
Arslan, Mikail; Saçkes, Zübeyde; Kaya, Mustafa Oğuzhan (Wiley-Blackwell, 2016)Hyaluronidases are excessively found in nature and involved innumerous biological functions. Hyaluronidases primarily degradehyaluronic acid (HA) and have significant role in fertilizationduring acrosomal reactions. ... -
In vitro effects of novel type M-V-O derivatives on Xanthine Oxidase
Kaya, Mustafa Oğuzhan; Gül, Gülşah Çelik; Kurtuluş, Figen (Cellular and Molecular Biology Association, 2017)Xanthine Oxidase (XO) is related with different diseases such as vascular, gout, nephropathy and renal stone diseases that are relevant to high uric acid levels and oxidative stress. Some common natural inhibitors of ... -
In vitro inhibition of purified human carbonic anhydrase I and II by novel fluorene derivatives
Demirhan, Hülya; Arslan, Mustafa; Kaya, Mustafa Oğuzhan; Kaya, Yeşim; Gençer, Nahit; Arslan, Oktay (Soc Chemists Technologists Madeconia, 2014)In this study, 9-benzylidene-9H-fluorene-substituted urea (5a-p) and thiourea derivatives (5q-v) were synthesized and their inhibitory effects on the activity of human carbonic anhydrase (hCA) I and II were evaluated. hCA ... -
Is there a relation between genetic susceptibility with cancer? A study about paraoxanase (PON1) enzyme activity in breast cancer cases
Kaya, Mustafa Oğuzhan; Sinan, Selma; Güler, Özen Özensoy; Arslan, Oktay (Taylor & Francis Ltd., 2016)Human serum paraoxonase 1 (PON1, EC 3.1.1.2) is a high density lipoprotein (HDL)-associated antioxidant enzyme that not only decreases oxidative stress, but it is also implicated in development of many cancers. Genetic ... -
Meme kanserli olgularda paraoksonaz (PON1) polimorfizminin belirlenmesi
Kaya, Mustafa Oğuzhan (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2009)Bu çalışmada, detoksifikasyon ve antioksidan aktivitelerine sahip insan serum Paraoksonaz 1 (PON1) enziminin meme kanserli olgularda aktivitelerinin türlemesi yapılarak kontrol grubuyla karşılaştırılmıştır. Bazal PON1 ... -
A new affinity method for purification of bovine testicular hyaluronidase enzyme and an investigation of the effects of some compounds on this enzyme
Terzi, Emine; Kaya, Mustafa Oğuzhan; Arslan, Oktay; Güler, Özen Özensoy (Wiley-Blackwell, 2015)In this study, a new affinity gel for the purification of bovine tes-ticular hyaluronidase (BTH) was synthesized. L-Tyrosine wasadded as the extension arm to the Sepharose-4B activated withcyanogen bromide. m-Anisidine is ... -
A new affinity method for purification of bovine testicular hyaluronidase enzyme and an investigation of the effects of some compounds on this enzyme
Kaya, Mustafa Oğuzhan; Arslan, Oktay; Güler, Özen Özensoy (Taylor & Francis Ltd, 2015)In this study, a new affinity gel for the purification of bovine testicular hyaluronidase (BTH) was synthesized. L-Tyrosine was added as the extension arm to the Sepharose-4B activated with cyanogen bromide. m-Anisidine ... -
Synthesis and carbonic anhydrase inhibitory properties of tetrazole- and oxadiazole substituted 1,4-dihydropyrimidinone compounds
Çelik, Fatma; Arslan, Mustafa; Kaya, Mustafa Oğuzhan; Yavuz, Emre; Gençer, Nahit; Arslan, Oktay (Informa Healthcare, 2014)A new series of tetrazole-, oxadiazole-and cyanosubstituted 1,4-dihydropyrimidinone compounds were synthesized, and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA) I were evaluated. ... -
Yeni bir metodla hyalüronidaz enziminin saflaştırılması ve bazı bileşiklerin bu enzim üzerine etkilerinin araştırılması
Kaya, Mustafa Oğuzhan (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2013)Hyalüronidaz enzimi, terapötik ve çeşitli tıbbi alanlarda bir yayılma faktörü olarak uygulanmaktadır. Geniş substrat özgüllüğünden dolayı, zincir uzunlukları değişen glikozaminoglikan oligosakaritlerinin hazırlanması gibi ...
