Browsing by Author "Korkmaz, Mehmet"
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Adeno virüslerle indüklenen, fare lenfositlerinin, (T.A.) hücrelerindeki mikro çekirdek indüksiyonunun belirlenmesi
Geçer, Özlem (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2003)İzmir Bölge Hıfzıssıhha Enstitüsü'ne gelen polio virüs şüpheli ve akut flask paralizi bulgusu bulunan veya temaslısı olan 24 kişiden alman gaita örneğinde yapılan ön çalışmalarda adeno virus tespit edildi. Bu izolatlar ... -
Effects of 5-aza-2 '-deoxycytidine on biological parameters of larval endoparasitoid Apanteles galleriae (Hymenoptera : Braconidae) and on its host Achoria grisella (Lepidoptera : Pyralidae)
Uçkan, Fevzi; Şengül, Şebnem Hepçorman; Sak, Olga; Korkmaz, Mehmet (Entomological Society America, 2007)The effects of 5-Aza-2'-deoxycytidine (5-Aza-dC), an inhibitor of DNA methyltransferase, were assessed on egg-to-adult developmental time, longevity, size, number of offspring produced, and sex ratio of the larval ... -
Increased cell proliferation and R.Msp1 fragmentation induced by 5-aza-2 '-deoxycytidine in rat testes related to the gene imprinting mechanism
Özdemir, Öztürk; Bulut, Hüseyin Eray; Korkmaz, Mehmet; Onarlioglu, Bilge; Çolak, Ahmet (Urban & Fischer Verlag, 2000)DNA methylation is one of the crucial mechanisms for cellular and tissue differentiation during developmental stages in mammals. 5-aza-2'-deoxycytidine, a specific cytosine DNA Methyltransferase inhibitor, is known to cause ... -
Monitoring of DNA damage in environmentally boron exposed people in Turkey by the alkaline comet assay
Korkmaz, Mehmet; Ündeğer, Ülkü; Aydın, Sevtap; Başaran, Nursen (Elsevier Ireland Ltd, 2007)Özet Yok -
N-Nitrosopirolidin (NPYR)'in farelerde sitogenetik etkileri
Korkmaz, Mehmet; Çolak, Ahmet (2000)N-Nitrosopirolidinin (Npyr) genotoksik aktivitesini değerlendirmek için, in vivo olarak fare kromozomlarına ve mikroçekirdek indüksiyonuna etkileri araştırılmıştır. Kromozom analizi için eşey ayrımı yapılmadan 10-12 haftalık ... -
Physiology, biochemistry, and topology: Effects of 5-Aza-2′-deoxycytidine on biological parameters of larval endoparasitoid Apanteles galleriae (Hymenoptera: Braconidae) and on its host Achoria grisella (Lepidoptera: Pyralidae
Uçkan, Fevzi; Şengül, Şebnem Hepçorman; Sak, Olga; Korkmaz, Mehmet (Entomological Society of America, 2007)The effects of 5-Aza-2′-deoxycytidine (5-Aza-dC), an inhibitor of DNA methyltransferase, were assessed on egg-to-adult developmental time, longevity, size, number of offspring produced, and sex ratio of the larval ... -
Possible role of k-ras oncogene in mutagenic activity of ethylnitrosourea on lymphocyte hyperproliferation in rat colon
N-ethyl-N-nitrosourea (ENU) is a potential carcinogenic agent that is commonly used in industry. Therefore the present study aimed to find out the possible effects of this agent on the rat digestive tract especially on the ... -
Treatment of ethylnitrosourea induced lymphocyte hyperproliferation by DNA hypomethylation in the rat colon
N-ethyl-N-nitrosourea (ENU) is a potential carcinogenic agent commonly used in industry, and it may cause an uncontrollable cell proliferation and eventually tumourgenesis. On the other hand, the hypomethilation of DNA by ...