Browsing by Author "Yay, Arzu"
Now showing items 1-17 of 17
-
Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury
Yazıcı, Alper; Aksit, Hasan; Sarı, Esin Söğütlü; Yay, Arzu; Erken, Haydar Ali; Akşit, Dilek; Çakmak, Harun; Seyrek, Kamil (Ijo Press, 2015)AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion (IR) model and compare pretreatment and post-treatment use. METHODS: Selenium pre-treatment group (n=8) was treated with intraperitoneal (i.p.) ... -
Does progesterone have protective effects on ovarian I/R injury?
Başer, Banu Güleç; Taşkın, Mine Islimye; Adalı, Ertan; Öztürk, Emine; Hişmioğulları, Adnan Adil; Yay, Arzu (Taylor & Francis Ltd, 2016)Context: There is number of studies about neuroprotective effects of progesterone against global cerebral ischemia/reperfusion (I/R) injury. Objective: The aim of the present study was to evaluate the protective effect ... -
Effect of 2-aminoethoxydiphenyl borate on ischemia-reperfusion injury in a rat ovary model
Taşkın, Mine İslimye; Hişmioğulları, Adnan Adil; Yay, Arzu; Adalı, Ertan; Güngör, Ayşenur Çakır; Korkmaz, Gözde Özge; İnceboz, Ümit (Elsevier Science Bv, 2014)Objective: The aim of this study is to evaluate the effects of 2-aminoethoxydiphenyl borate (2-APB) as an antioxidant and analyze biochemical and histopathologic changes in experimental ischemia-reperfusion (I/R) injury ... -
The effects of ozone therapy on caspase pathways, TNF-alpha, and HIF-1 alpha in diabetic nephropathy
Güçlü, Aydın; Erken, Haydar Ali; Erken, Gülten; Dodurga, Yavuz; Yay, Arzu; Özçoban, Özge; Simsek, Hasan; Akcılar, Aydın; Koçak, Fatma Emel (Springer, 2016)Accelerated apoptosis plays a vital role in the development of diabetic vascular complications. Ozone may attenuate diabetic nephropathy by means of decreased apoptosis-related genes. The aim of our study was to investigate ... -
Evaluation of therapeutic potential of intraperitoneal ozone gas in combination with insulin above cranial and spinal neuropathy in rats with diabetes mellitus
Karademir, Mustafa; Sönmez, Mehmet Akif; Akçilar, Raziye; Koçak, Emel; Yay, Arzu; Eser, Olcay (Comenius Univ, 2018)OBJECTIVE: This study aimed to investigate the therapeutic effect of ozone in combination with insulin on cranial and spinal neuropathy in rats with diabetes mellitus (DM). MATERIALS AND METHODS: Sixty adult male Sprague ... -
Fellow eye involvement in retinal ischemia reperfusion injury
Yazıcı, Alper; Sarı, Esin; Yay, Arzu; Akşit, Hasan; Erken, Haydar Ali; Kılıç, Adil; Ermiş, Samet (2014)Purpose: To evaluate histologic changes in the fellow non-ischemic eye retina in ischemia reperfusion (IR) injury and compare with control group retina. Materials and Methods: Sixteen male Wistar-Albino rats weighing 200-250 ... -
A humanized anti-ınterleukin 6 receptor monoclonal antibody, tocilizumab, for the treatment of endometriosis in a rat model
Taşkın, Mine Islimye; Güngör, Ayşenur Çakır; Adalı, Ertan; Yay, Arzu; Önder, Gözde Özge (Sage Publications Inc, 2016)Objective: The aim of this study was to investigate the efficacy of anti-interleukin 6 (IL-6) therapy in the treatment of endometriosis in a rat model. Study Design: After the peritoneal implantation of autologous endometrial ... -
Inhibitory effect of sub-conjunctival tocilizumab on alkali burn induced corneal neovascularization in rats
Sarı, Esin Söğütlü; Yazıcı, Alper; Akşit, Hasan; Yay, Arzu; Şahin, Gözde; Yıldız, Onur; Ermiş, Sıtkı Samet; Seyrek, Kamil; Yalçın, Betül (Taylor & Francis Inc, 2015)Background: To evaluate the effects of sub-conjunctivally applied interleukin-6 receptor (IL-6R) antibody (tocilizumab) on alkali burn induced corneal neovascularization (CNV) in rats. Methods: Alkali burn induced corneal ... -
Nephrotoxic effects of varenicline as the most effective drug used for smoking cessation: A preliminary experimental study
Koç, Akif; Erken, Haydar Ali; Koçak, Fatma Emel; Yay, Arzu; Güçlü, Aydin; Sarı, Erhan; Şimşek, Hasan; Önder, Gözde Özge (Springer, 2015)Varenicline is a new most effective drug for smoking cessation. Its effect on kidney functions remains unclear. This study purposed to investigate whether varenicline causes nephrotoxicity in rats. Fifteen rats were randomly ... -
Prevention of ovarian hyperstimulation syndrome in a rat model: comparison of the efficacy of tocilizumab with that of ranibizumab, cabergoline, and a gonadotropin-releasing Hormone antagonist
Taşkın, Mine İslimye; Topçu, Onur; Yay, Arzu; Erken, Gülten; Balcıoğlu, Esra; Adalı, Ertan; Hişmioğulları, Adnan Adil (Taylor & Francıs Ltd, 2015)The aim of the study is to investigate the effects of the interleukin-6 (IL-6) blocker tocilizumab in a hyperstimulated rat model and compare it with ranibizumab, a gonadotropin-releasing hormone antagonist (GnRHA), and ... -
Progesterone decreases the extent of ovarian damage caused by cisplatin in an experimental rat model
Özdamar, Saim; Taşkın, Mine İslimye; Önder, Gözde Özge; Kaymak, Emin; Baran, Münevver; Yay, Arzu (Wroclaw Medical Univ, 2019)Background. Apart from the role of progesterone in reproductive physiology, the protective role of exogenously administered progesterone was observed in various injuries, such as neurologic defects and acute kidney ... -
Protective effect of 2-apb on testicular ischemia-reperfusion injury in rats
Sarı, Erhan; Akşit, Hasan; Erken, Haydar Ali; Yay, Arzu; Akşit, Dilek; Amasyalı, Akın Soner; Yıldız, Onur; Küçükyangöz, Ahmet (Lippincott Williams & Wilkins, 2015)Purpose: We performed biochemical and histopathological evaluations to assess the effects of 2-APB on ischemia-reperfusion induced testicular damage. Materials and Methods: A total of 28 rats were randomly divided into ... -
The protective effect of selenium in cisplatin-related retinotoxicity
Yazıcı, Alper; Sarı, Esin Sögütlü; Yay, Arzu; Kılıç, Adil; Akşit, Dilek; Akşit, Hasan; Yıldız, Onur; Ermiş, Sıtkı Samet (Taylor & Francıs Ltd, 2014)Purpose: The aim of this study is to evaluate the retinal toxicity of cisplatin and neuroprotective effect of selenium in cisplatin-related retinal toxicity. Methods: Eighteen adult Wistar-Albino rats were divided into ... -
Protective effects of sildenafil citrate administration on cisplatin-induced ovarian damage in rats
Taşkın, Mine İslimye; Yay, Arzu; Adalı, Ertan; Balcıoğlu, Esra; İnceboz, Ümit (Informa Healthcare, 2015)The aim of this study is to evaluate the effects of sildenafil citrate on cisplatin-induced ovarian toxicity. Thirty-two female rats were divided into four groups. Group 1: saline control; group 2: cisplatin; group 3: ... -
Selenium partially prevents cisplatin-induced neurotoxicity: A preliminary study
Erken, Haydar Ali; Koç, Emine Rabia; Yazıcı, Haşmet; Yay, Arzu; Önder, Gözde Özge; Sarıcı, Saim Furkan (Elsevier Science Bv, 2014)Cisplatin is an anticancer drug and it has neurotoxic effects. On the other hand, the neuroprotective effect of selenium was observed in previous studies. However, the effect of selenium on cisplatin-induced neurotoxicity ... -
Selenium protects retinal cells from cisplatin-induced alterations in carbohydrate residues
Akşit, Dilek; Yazıcı, Alper; Akşit, Hasan; Sarı, Esin Söğütlü; Yay, Arzu; Yıldız, Onur; Kılıç, Adil; Ermiş, Sıtkı Samet; Seyrek, Kamil (Galenos Yayincilik, 2016)Background: Investigate alterations in the expression and localization of carbohydrate units in rat retinal cells exposed to cisplatin toxicity. Aims: The aim of the study was to evaluate putative protective effects of ... -
Surgical procedures required for measurement reduce nerve conduction velocity: An in vivo and in vitro comparative study
Erken, Haydar Ali; Erken, Gülten; Yay, Arzu; Göktepe, Özge (Taylor & Francis Inc, 2021)Background: Although in vitro methods have disadvantages, they are still commonly used to measure nerve conduction velocity (NCV) in experimental studies. Therefore, this study was designed to demonstrate the effect of the ...
