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Synthesis and biological evaluation of new 4-thiazolidinone derivatives as carbonic anhydrase inhibitors
(Bentham Science Publ Ltd, 2017)
Background: The catalytically active site of CA enzyme is Zn (II) bound hydroxide ion part which acts as a strong nucleophile (at neutral pH) on the CO2 molecule bound in a hydrophobic pocket nearby. We designed a series ...
The determination of effect of some antibiotics on paraoxonase 2 (PON2) enzyme activities in human macrophages cell
(Wiley-Blackwell, 2015)
The human paraoxonase (hPON) gene family includes threemembers: PON1, PON2, and PON3, located adjacent to eachother on the long arm of chromosome 7. The three hPONs shareapproximately 65% identity at the amino acid level ...
Synthesis, structure-activity relationships and biological activity of new isatin derivatives as tyrosinase ınhibitors
(Bentham Science Publ Ltd, 2014)
A newly series of isatin derivatives (6a-t) containing alkyl/aryl urea groups were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. Tyrosinase was purified from ...
In vitro effects of some herbicides and fungicides on human erythrocyte carbonic anhydrase activity
(Parlar Scientific Publications (P S P), 2012)
The effects of Imazethapyr, 2,4-D dimethylamine salt, Glyphosate isopropylamine salt and Propamocarb HCl, which are commonly used in agricultural fields, have been investigated on human erythrocyte carbonic anhydrase ...
The determination of the carbonic anhydrases activators in vitro effect of mixed donor crown ethers
(Wiley, 2018)
Carbonic anhydrases (CAs) play an important function in various physiological and pathological processes. Therefore, many researchers work in this field in order to design and synthesize new drugs. Both inhibitors and ...
Enzymatic browning in foods and its prevention
(Nova Science Publishers, 2009)
Phenolic compounds are widely distributed in the plant kingdom and are considered to be secondary metabolites. Structurally they contain an aromatic ring bearing one or more hydroxyl groups, together with a number of other ...
Inhibition kinetic of Ocimum basilicum L. polyphenol oxidase
(Walter De Gruyter Gmbh, 2007)
The paper reports the inhibition model of the purified polyphenol oxidase (PPO) activity from basil (Ocimum basilicum L.) with L-cysteine, ethylenediaminetetraacetic acid (EDTA), ascorbic acid, gallic acid, D,L-dithiothreitol, ...
Carbonic anhydrase from Cyprinus carpio
(Elsevier GMBH, 2003)
Carbonic anhydrase (CA) is the basic enzyme in the breathing function and catalyses the reversible hydration of CO2 to HCO3- and H+.A method is introduced to purify the carbonic anhydrase from erythrocytes of the carp ...
Köpek aritrositlerinden afinite kromatografisi ile saflaştırılan karbonik anhidraz enziminin sülfonamidlerle inhibisyon kinetiğinin incelenmesi.
(Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2005)
% 15-20 oranı ile körlüğe en çek yol açan göz hastalıklarından birisi olan glokom hastalığında karbonik anhidraz enzimi, hastalığı tetikleyici bir etkiye sahiptir. Bu nedenle glokom hastalığının tedavisinde yıllardan beri ...
Cynara scolymus L. bitkisinden elde edilen polifenol oksidaz enziminin kinetik özelliklerinin araştırılması
(Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2004)
Bu çalışmada, enginardan (Cynara scolymus L.) polifenoloksidaz (PFO) enzimi amonyum sülfat çöktürmesi ve diyaliz işlemleri ile kısmen saflaştırılmıştır. Enginar ekstraktlanmn toplam fenolik madde içeriği Folin-Ciocalteau ...
