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Expression analysis of URG4 (upregulated gene 4) in osteoblast-like cells, Saos-2 and MG63
(Wiley-Blackwell, 2011)
URG4 is a novel gene firstly found in uninfected liver cells stimu-lated by HBxAg (Hepatitis B virus encoded X antigen) and HCC(Hepatocellular Carcinoma) cells. It is associated with cellgrowth, growth factor-independent ...
Effects of fibroblast growth factor (FGF acidic) and epidermal growth factor (EGF) on procollagen-N proteinases; ADAMTS-2 and ADAMTS-3 in osteosarcoma model
(Wiley-Blackwell, 2012)
A Disintegrin and Metalloproteinase domain, with Thrombo-Spondin (ADAMTS) is a family of zinc-dependent proteases thathave common features with A Disintegrin and Metalloproteinase(ADAM) and also MMP enzymes (Matrix ...
Evaluation of in vitro effects of some analgesic drugs on erythrocyte and recombinant carbonic anhydrase I and II
(Informa Healthcare, 2012)
The in vitro effects of the injectable form of analgesic drugs, dexketoprofen trometamol, dexamethasone sodium phosphate, metamizole sodium, diclofenac sodium, thiocolchicoside, on the activity of purified human carbonic ...
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase ii: influences on the catalytic activity and affinity for inhibitors
(Pergamon-Elsevier Science Ltd, 2012)
Site-directed mutagenesis has been used to change three amino acid residues involved in the binding of inhibitors (Asn67Ile; Gln92Val and Leu204Ser) within the active site of human carbonic anhydrase (CA, EC 4.2.1.1) II ...
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models
(Elsevier Science, 2018)
ADAMTS3 is a member of procollagen N-proteinase subfamily of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) gene family. It has an important function in the procollagen maturation process. The ...
Molecular characterization of zeta class glutathione s-transferases from pinus brutia ten.
(Indian Acad Sciences, 2015)
Glutathione transferases (GSTs; EC 2.5.1.18) play important roles in stress tolerance and metabolic detoxification in plants. In higher plants, studies on GSTs have focussed largely on agricultural plants. There is restricted ...
Induction of human ADAMTS-2 gene expression by IL-1 alpha is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells
(Elsevier Science BV, 2015)
Up-regulation of ADAMTS genes with proinflammatory cytokines is important for some pathological conditions such as osteoarthritis (OA) that is a disease based on ECM degradation in cartilage. IL-1 alpha is a proinflammatory ...
IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathwa
(Springer, 2014)
ADAMTS-2 and ADAMTS-3 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 2) belong to the procollagen aminoproteinase subfamily of ADAMTS proteases. They play crucial roles in the collagen metabolism. ...
Molecular cloning and biochemical characterization of a Tau class glutathione S-transferase from Pinus brutia Ten
(Springer Heidelberg, 2020)
Key message A new Tau class GST gene was cloned from Pinus brutia Ten. cDNA sequence was analysed for conserved sequences. Substrate specificity, optimum pH, and temperature values of the recombinant PbGST Tau enzyme were ...
