Search
Now showing items 1-10 of 21
Cloning and expression of human CAI in E-coli
(Blackwell Publishing,, 2006)
yok
Site-directed mutagenesis of Asn67/IIe67 in human CAII and expression of mutant protein in E-coli
(Blackwell Publishing, 2006)
yok
Saccharomyces cerevisiae beta-carbonic anhydrase: ınhibition and activation studies
(Bentham Science Publ Ltd, 2010)
The beta-carbonic anhydrase from Saccharomyces cerevisiae (CA, EC 4.2.1.1), scCA, which is encoded by the Nce103 gene, is an effective catalyst for CO2 hydration to bicarbonate and protons, with a k(cat) of 9.4 x 10(5) ...
Evaluation of in vitro effects of some analgesic drugs on erythrocyte and recombinant carbonic anhydrase I and II
(Informa Healthcare, 2012)
The in vitro effects of the injectable form of analgesic drugs, dexketoprofen trometamol, dexamethasone sodium phosphate, metamizole sodium, diclofenac sodium, thiocolchicoside, on the activity of purified human carbonic ...
Comparison of hydratase, esterase activities and inhibition manner of mutant Asn67/Ile and Leu204/Ser of human CAII
(Blackwell Publishing, 2008)
Carbonic anhydrases (CAs; also known as carbonate dehydratases EC 4.2.1.1)
are a family of enzymes which catalyze the reversible reaction from H2O and
CO2 to HCO3
- ions. Carbonic anhydrases are ubiquitous metalloenzymes ...
Inhibition studies on mutant Phe91Asn human carbonic anhydrase I (HCA I) gene
(Wiley-Blackwell, 2008)
Carbonic anhydrases (CAs; carbonate dehydratases EC 4.2.1.1) are
ubiquitous metalloenzymes present in prokaryotes and eukaryotes that
and encoded by four evolutionarily different gene families. In mammals, 15 a-CA isozymes ...
Effects of some antibiotics on paraoxonase from human serum in vitro and from mouse serum and liver in vivo
(Pharmaceutical Soc Japan, 2006)
Paraoxonase (PON1, EC 3.1.8.1) is an esterase protein which plays multifunctional role in metabolism. Therefore, in this study the effects of commonly used antibiotics, namely sodium ampicillin, ciprofloxacin, rifamycin ...
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions
(Pergamon-Elsevier Science Ltd, 2008)
The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase (CA, EC 4.2.1.1) designated as scCA, has been cloned, purified, characterized kinetically, and investigated for its inhibition ...
Differential in vitro inhibition effects of some antibiotics on tumor associated carbonic anhydrase isozymes of hCA-IX and hCA-XII
(Informa Healthcare, 2008)
Hypoxia is a common characteristic of locally advanced solid tumors that has been associated with diminished therapeutic response and malignant progression. Human carbonic anhydrase (hCA) hCA IX and XII isozymes are tumor ...
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase ii: influences on the catalytic activity and affinity for inhibitors
(Pergamon-Elsevier Science Ltd, 2012)
Site-directed mutagenesis has been used to change three amino acid residues involved in the binding of inhibitors (Asn67Ile; Gln92Val and Leu204Ser) within the active site of human carbonic anhydrase (CA, EC 4.2.1.1) II ...
