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Transcription of the PSMD4 gene is upregulated in hypoxia in prostate cancer cells
(Wiley-Blackwell, 2015)
ThePSMD4(Proteosome 26S non-ATPase subunit 4) gene islocated human chromosome 1. This gene encodes three proteins,namely S5A, antisecretory factor (ASF) and Angiocidin. S5a isthe polyubiquitin binding subunit of the 26S ...
Differential in vitro inhibition effects of some antibiotics on tumor associated carbonic anhydrase isozymes of hCA-IX and hCA-XII
(Informa Healthcare, 2008)
Hypoxia is a common characteristic of locally advanced solid tumors that has been associated with diminished therapeutic response and malignant progression. Human carbonic anhydrase (hCA) hCA IX and XII isozymes are tumor ...
Differential in vitro inhibitory effects of anticancer drugs on tumor-associated carbonic anhydrase isozymes CA IX and CA XII
(Prous Science, 2008)
Carbonic anhydrase IX (CA IX) and, to a lesser extent. carbonic anhydrase XII (CA XII) are highly overexpressed in hypoxic tumors. In this study, the inhibitory effects of 11 different anticancer drugs including paclitaxel, ...
Tgf-beta upregulates tumor-associated carbonic anhydrase IX gene expression in Hep3B cells
(Wiley, 2009)
Carbonic anhydrase IX (CAIX) is a membrane-associated carbonic anhydrase (CA) that is overexpressed in a variety of tumor types and associated with increased metastasis, giving a poor prognosis. Transcriptional regulation ...
SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells
(Elsevier Science Bv, 2016)
ADAM metallopeptidase with thrombospondin type I motif, 1 (ADAMTS1) that has both antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic circumstances. However, there is limited information ...
Upregulation of PSMD4 gene by hypoxia in prostate cancer cells
(Tubitak Scientific & Technical Research Council Turkey,, 2020)
Ubiquitin-proteasome pathways have a crucial role in tumor progression. PSMD4 (Rpn10, 26S proteasome non-ATPase subunit 4), which is a subunit of the regulatory particle, is a major ubiquitin (Ub) receptor of 26S proteasome. ...
Carbonic anhydrase III is a new target of HIF1 alpha in prostate cancer model
(Elsevier, 2020)
Carbonic Anhydrase III (CAIII) belongs to a member of the alpha Carbonic Anhydrase (CA) family. Although some CA members are strongly up-regulated by HIF1-alpha, it is not known about the transcriptional regulation of CAIII ...
