Browsing Kimya-Diğer Yayınlar Koleksiyonu by Publisher "Bentham Science Publ Ltd"
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Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII
(Bentham Science Publ Ltd, 2010)The carbonic anhydrase (CA, EC 4.2.1.1) isozymes IX and XII are predominantly found in tumor cells and show a restricted expression in normal tissues. By efficiently hydrating carbon dioxide to protons and bicarbonate, ... -
Saccharomyces cerevisiae beta-carbonic anhydrase: ınhibition and activation studies
(Bentham Science Publ Ltd, 2010)The beta-carbonic anhydrase from Saccharomyces cerevisiae (CA, EC 4.2.1.1), scCA, which is encoded by the Nce103 gene, is an effective catalyst for CO2 hydration to bicarbonate and protons, with a k(cat) of 9.4 x 10(5) ...