Browsing Kimya-Makale Koleksiyonu by Subject "Benzenesulfonamide"

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4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII

Khloya, Poonam; Çelik, Gülşah; SitaRam; Vullo, Daniela; Supuran, Claudiu T.; Sharma, Pawan K. (Elsevier France-Editions Scientifiques Medicales Elsevie, 2014)

A library of 4-functionalized 1,3-diarylpyrazoles (3a-3h, 5a-5g and 6a-6g) was designed, synthesized and evaluated against four human carbonic anhydrase (CA, EC 4.2.1.1) isozymes representing two cytosolic isozymes hCA I ...
Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII

SitaRam; Çelik, Gülşah; Khloya, Poonam; Vullo, Daniela; Supuran, Claudiu T.; Sharma, Pawan K. (Pergamon-Elsevier Science Ltd, 2014)

Three series of novel heterocyclic compounds (3a-3g, 4a-4g and 5a-5g) containing benzenesulfonamide moiety and incorporating a 1,2,4-triazole ring, have been synthesized and investigated as inhibitors against four isomers ...