Browsing Biyoloji-Diğer Yayınlar Koleksiyonu by Title

The effect of sodium tetraborate on antioxidant enzymes

Doğan, Serap; Alan, Ümran; Doğan, Mehmet; Bozdemir, Kazım (Wiley-Blackwell, 2012)

Antioxidant enzymes have main role in the defense of mamma-lian blood. Experimental investigations have repeatedly shownthat erythrocytes are particularly sensitive to oxidative stres. Forthis purpose, thein vitrobiochemical ...

Effect of vascular endothial growth factor (VEGF) on ADAMTS1 gene expression in hepatoma cells

Günerhan, Kubilay Tuğrul; Yıldırım, Hatice; Sunay, Fatma Bahar; Türkoğlu, Sümeyye Aydoğan; Köçkar, Feray (Wiley-Blackwell, 2013)

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Effects of fibroblast growth factor (FGF acidic) and epidermal growth factor (EGF) on procollagen-N proteinases; ADAMTS-2 and ADAMTS-3 in osteosarcoma model

Alper, Meltem; Köçkar, Feray (Wiley-Blackwell, 2012)

A Disintegrin and Metalloproteinase domain, with Thrombo-Spondin (ADAMTS) is a family of zinc-dependent proteases thathave common features with A Disintegrin and Metalloproteinase(ADAM) and also MMP enzymes (Matrix ...

Effects of some pesticides on catalase and glutation s-transferase in cyprinus carpio carpio

Karasakal, Ömer Faruk; Alan, Ümran; Diken, Mehmet Emin; Bozdemir, Kadir; Güngör, Nurten; Doğan, Serap (Wiley-Blackwell, 2012)

Free radicals which known reactive oxygen species (ROS) have changing capasity biomolecules like lipids, nucleic acids, considerably reactive and unstabile metabolites. Biological sistems in body developed defence system ...

Effects of TGF-beta and TNF-alpha on the expression of tumour-related CAXII and CAIX in prostate tumour cell line, PC3

Selçuk, Gökçe; Yıldırım, Hatice Kalkan; Sağkan, Rahsan İlikçi; Köçkar, Feray; Karaman, Musa (Wiley-Blackwell, 2011)

Cancer is the one the most important health problem of today’sand because of the high death risk and being so widespread, ithas became to public health disease. Cancer is described asuncontrolled cell proliferation and ...

The effects of TNF-alpha on ADAMTS-1 and VEGF gene expressions in HEP3B cells

Sunay, Fatma Bahar; Türkoğlu, Sümeyye Aydoğan; Köçkar, Feray (Wiley-Blackwell, 2012)

Angiogenesis is essential for tumor growth, progression andmetastasis. Angiogenesis is controlled by several endogenousstimulators and inhibitors. Among these stimulators, the vascularendothelial growth factor (VEGF) owns ...

Effects of vascular endothelial growth factor (VEGF) on CAIX expression in Hep3B cells

Avcıkurt, Ayla Solmaz; Köçkar, Feray; Yıldırım, Hatice (Wiley-Blackwell, 2012)

Zinc containing carbonic anhydrase enzymes have important rolesin different physiological processes as gas exchange, ion transportand acid-base balance. Carbonic anhydrases catalyse the reversiblereaction from H2OandCO2to ...

Expression analysis of URG4 (upregulated gene 4) in osteoblast-like cells, Saos-2 and MG63

Köçkar, Feray; Tokay, Esra; Alper, Meltem (Wiley-Blackwell, 2011)

URG4 is a novel gene firstly found in uninfected liver cells stimu-lated by HBxAg (Hepatitis B virus encoded X antigen) and HCC(Hepatocellular Carcinoma) cells. It is associated with cellgrowth, growth factor-independent ...

Expression of carbonic anhydrase III (CAIII) from different cell lines

Okuyan, D.; Türkoğlu, Sümeyye Aydoğan; Köçkar, Feray (Wiley-Blackwell, 2011)

Carbonic anhydrase III (CAIII, Carbonate Dehydratase EC 4.2.1)is an abundant cytoplasmic protein found in skeletal muscle, liver,and adipocytes. It is distinguished from other members of the CAfamily by characteristics ...

The expressions of ADAMTS-1 and VEGF inDU-145, PC-3, MCF-7 and HT-29 cell lines

Sunay, Fatma Bahar; Türkoğlu, S. Aydoğan; Köçkar, Feray; Okuyan, D. (Wiley-Blackwell, 2010)

The formation of new blood vessels from preexisting capillariesby the invasion and sprouting of the endothelial cells is called asangiogenesis. Angiogenesis is essential for tumor growth, progres-sion and metastasis. Several ...

Hipoksi ve kanser

Türkoğlu, Sümeyye Aydoğan; Poyrazlı, Fatma; Okuyan, Derya; Köçkar, Feray (Çanakkale Onsekiz Mart Üniversitesi Fen Bilimleri Enstitüsü, 2021)

Dokudaki gerekli oksijen seviyesinin normal değerin altına düşmesi hipoksi olarak tanımlanır. Hipoksi katı tümörlerde sık karşılaşılan bir durumdur. Tümör hücreleri yeterli oksijen alamadığında hücre ölümüne gitmeden ...

Immobilization of Carbonic anhydrase II (CAII) enzyme on superparamagnetic iron-oxide nanoparticles

Türkoğlu, Sümeyye Aydoğan; Karaağaç, Özlem; Köçkar, Feray; Köçkar, Hakan; Okuyan, Derya (Wiley-Blackwell, 2013)

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Immobilization of Olive beta-glucosidase on to superparamagnetic nanoparticules and its characterization

Savaş, Elif; Onat, Serhat; Kaya, Y. M.; Köçkar, Hakan; Köçkar, Feray (Wiley-Blackwell, 2013)

Covalently binding of Olive b-glucosidase that active on the main olive phenolic glycosides, to superparamagnetic magnetite nano- particles via carbodiimide actiyatian was investigated and pre- sented in this study. The ...

Inhibition of monoamineoxidase a (Mao-a) by some herbal medicines

Güngör, Nuran; Doğan, Serap; Alan, Ümran; Yılmaz, Begümhan (Wiley-Blackwell, 2015)

In this study, the inhibition effects ofHypericum perforatumL.,Ginkgo bilobaL., Lavandula angustifoliaMiller,Zingiber offici-naleRoscoe,Tilia tomentosaMoench.,Cinnamomum aromaticumJ. Graham, Menthae piperitaL.,Thymus ...

Inhibition studies on mutant Phe91Asn human carbonic anhydrase I (HCA I) gene

Köçkar, Feray; Ayduen, M.; Türkoğlu, Sümeyye Aydoğan; Arslan, Oktay; Turan, Yusuf (Wiley-Blackwell, 2008)

Carbonic anhydrases (CAs; carbonate dehydratases EC 4.2.1.1) are ubiquitous metalloenzymes present in prokaryotes and eukaryotes that and encoded by four evolutionarily different gene families. In mammals, 15 a-CA isozymes ...

Inhibition types and some kinetic properties of tyrosinase of deepwater pink shrimp (Parapenaeus longirostris) from edremit bay

Diken, Mehmet Emin; Doğan, Serap; Alan, Ümran; Doğan, Mehmet (Wiley-Blackwell, 2012)

Phenoloxidases (POs) are a family of enzymes including tyrosin-ases, catecholases and laccases, which play an important role inimmune defence mechanisms in various invertebrates. The aim ofthis study was to identify the ...