Yazar "Önal, Gizem" için listeleme
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Body weight modulates the impact of oxytocin on chronic cold-immobilization stress response
Önal, Deniz; Korkmaz, Hilal; Önal, Gizem; Pehlivanoğlu, Bilge (Elsevier Inc., 2024)By activating the stress system, stress modulates various physiological parameters including food intake, energy consumption, and, consequently, body weight. The role of oxytocin in the regulation of stress and obesity ... -
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.815G > A (p.R272Q) or c.1348C > T (p. R450C) in the RHOT1 gene encoding Miro1
Chemla, Axel; Arena, Giuseppe; Önal, Gizem; Walter, Jonas; Berenguer-Escuder, Clara; Grossmann, Dajana; Grunewald, Anne; Schwamborn, Jens C.; Kruger, Rejko (Elsevier, 2023)Fibroblasts from two Parkinson's disease (PD) patients carrying either the heterozygous mutation c.815G > A (Miro1 p.R272Q) or c.1348C > T (Miro1 p.R450C) in the RHOT1 gene, were converted into induced pluripotent stem ... -
Impairment of lipophagy by PNPLA1 mutations causes lipid droplet accumulation in primary fibroblasts of autosomal recessive congenital ichthyosis patients
Önal, Gizem; Kutlu, Özlem; Özer, Ebru; Gözüaçık, Devrim; Karaduman, Ayşen; Emre, Serap Dökmeci (Elsevier Ireland LTD, 2019)Background: Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of epidermal keratinization disorders. One of the disease-associated proteins, patatin-like phospholipase domain-containing protein-1 (PNPLA1), plays ... -
Molecular genetic analysis of Turkish Gaucher's disease patients reveals three novel variants in Glucocerebrosidase (GBA) gene
Önal, Gizem; Gümüş, Ersin; Demir, Hülya; Yüce, Aysel; Dökmeci, Serap Emre (Elsevier, 2020)Gaucher's disease (GD) is the most prevalent lysosomal storage disorder caused by the deficiency of beta-gluco-sylceramidase enzyme (EC 3.2.1.45) due to mutations in the GBA gene. To date, more than 400 GBA mutations have ...
