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Selagibenzophenone b and its derivatives: Selb-1, a dual topoisomerase I/II inhibitor identified through in vitro and in silico analyses

Dönmez, Serhat; Lapinskaite, Ringaile; Atalay, Hazal Nazlıcan; Tokay, Esra; Köçkar, Feray; Rycek, Lukas; Özbil, Mehmet; Tumer, Tuğba Boyuneğmez (American Chemical Society, 2024)

The development of multitargeted drugs represents an innovative approach to cancer treatment, aiming to enhance drug effectiveness while minimizing side effects. Herein, we sought to elucidate the inhibitory effect of ...