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Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro

Sinan, Selma; Köçkar,Feray; Gençer, Nahit; Yıldırım, Hatice Kalkan; Arslan, Oktay (Maik Nauka/Interperiodıca/Springer, 2006)

Human serum paraoxonase (hPON 1) was separately purified by ammonium sulfate precipitation and hydrophobic interaction chromatography The in vitro effects of commonly used antibiotics, namely clarithromycin and chloramphenicol, ...