Güncel Gönderiler: Klinik Öncesi Bilimler Bölümü
Toplam kayıt 118, listelenen: 61-80
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The protective effect of metformin in scopolamine-induced learning and memory impairment in rats
(Polish Acad Sciences Inst Pharmacology, 2019)Background: Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. One of the most commonly prescribed oral antidiabetic drug, metformin, has been shown to have beneficial effects on restoring ... -
Expression of serotonin 2A, 2C, 6 and 7 receptor and İL-6 mrna in experimental toxoplasmic encephalitis in mice
(Elsevier Sci LTD, 2019)The neurotropic pathogen Toxoplasma gondii infects about one-third of the human population. Both acute and chronic (latent or life-long) forms of toxoplasmosis are associated with specific neurologic and neuropsychiatric ... -
The acute effect of commercial "energy drink" on hematological, biochemical and strength parameters induced by eccentric contractions
(Ios Press, 2013)BACKGROUND: Commercial energy drink usage is reported to be higher in athletes and adolescents. However, the impact of pre-exercise consumption of energy beverages on hematologic and biochemical responses and skeletal ... -
Effects of N-acetyl cysteine on glutathione metabolism and lipid peroxidation in the experimental hepatic intoxication
(Ankara Univ Press, 2015)In this study, the effects of intraperitoneal applications N-acetyl cysteine (NAC) an glutathione (GSH) precursor, on GSH and related enzymes, lipid peroxidation activities in the erythrocyte and liver tissue were investigated. ... -
The protective effect of resveratrol in experimentally induced non-sterile clean wound inflammation in rats
(Kafkas Univ, 2013)The effects of resveratrol on haematological and biochemical parameters were investigated in rats that had inflammation induced by experimental non-sterile clean wound technique. Twenty four male Wistar-Albino rats weighing ... -
The effect of surgery (Ovariohysterectomy) on the plasma disposition of meloxicam following intravenous administration in dogs
(BMC, 2016)Background: Meloxicam (MLX) is a nonsteroidal anti-inflammatory drug used in the relief of postoperative pain for human and veterinary medicine. This study was designed to investigate the effect of surgery on the plasma ... -
Protective effect of 2-apb on testicular ischemia-reperfusion injury in rats
(Lippincott Williams & Wilkins, 2015)Purpose: We performed biochemical and histopathological evaluations to assess the effects of 2-APB on ischemia-reperfusion induced testicular damage. Materials and Methods: A total of 28 rats were randomly divided into ... -
Plasma disposition, milk excretion and parasitological efficacy of mebendazole in donkeys naturally infected by Cyathostominae
(Elsevier Sci Ltd, 2016)Mebendazole (MBZ) has been licensed for use in horses and donkeys, however there are no data available in the literature regarding its pharmacokinetic disposition and efficacy in donkeys. This study was designed to determine ... -
Lycopene ameliorates experimental colitis in rats via reducing apoptosis and oxidative stress
(Verlang Hans Huber, 2016)Inflammatory bowel disease (IBD) is an inflammatory disorder involving colitis. Lycopene is a naturally occurring carotenoid that has attracted considerable attention as a potential chemopreventive agent. The impact of ... -
The effect of amniotic membrane on serum biochemical parameters in experimentally induced non-sterile clean wound inflammation
(Kafkas Univ, 2012)The effect of amniotic membrane on biochemical parameters was investigated in response to experimentally induced non-sterile clean wound inflammation. In addition, the effort was made to find out the biochemical compounds ... -
A case of tuberculosis in a free-living long-legged buzzard (buteo rufinus)
(Kafkas Üniv, 2016)A male Long-legged buzzard with a gunshot wound on his left wing was presented for treatment. However, the bird died shortly after, and then the routine necropsy was performed. At necropsy, numerous white-to-yellow nodular ... -
Plasma disposition and faecal excretion of eprinomectin following topical and subcutaneous administration in non-lactating dairy cattle
(Taylor & Francis Inc, 2016)AIMS: To investigate the plasma disposition and faecal excretion of eprinomectin (EPM) in non-lactating dairy cattle following topical and S/C administration.METHODS: Holstein dairy cows, 3.5-5 years-old, were selected ... -
Oleuropein ameliorates arsenic induced oxidative stress in mice
(Elsevier GMBH, 2016)The objective of this study is to investigate the potential preventive effect of oleuropein in an experimental arsenic toxicity in mice. For this purpose, mice were exposed to 5 mg/kg/day sodium arsenite (NaAsO2) in drinking ... -
Protective effects of n-acetyl cysteine on oligosaccharide residues in the experimental liver intoxication formed by carbontetrachloride (ccl4) in rats
(Carbone Editore, 2016)Aim: In this study, we aimed to investigate the protective effects of N-acetyl cysteine (NAC) that is known playing an important role in detoxification reactions of biomolecules, on rat liver tissue exposed to carbon ... -
Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury
(Ijo Press, 2015)AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion (IR) model and compare pretreatment and post-treatment use. METHODS: Selenium pre-treatment group (n=8) was treated with intraperitoneal (i.p.) ... -
Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats
(BMC, 2015)Background: The aims of this study were to compare the pharmacokinetics of albendazole sulfoxide (ABZ-SO, ricobendazole) in goats and sheep at a dose of 5 mg/kg bodyweight (BW), after intravenous (IV) and subcutaneous (SC) ... -
The protective effect of curcumin administration on carbon tetrachloride (ccl4)-induced nephrotoxicity in rats
(Polish Acad Sciences Inst Pharmacology, 2015)Background: The aim of the present study was to examine the protective effect of curcumin (CUR) on carbon tetrachloride (CCl4)-induced nephrotoxicity to evaluate the detailed mechanisms by which CUR exerts its protective ... -
Protective effect of 2-aminoethyl diphenylborinate in rat colitis model induced by acetic acid
(E-Century Publishing Corp, 2016)Some of the diseases like ulcerative colitis, Crohn disease and certain types of intestinal cancers are not treatable effectively. Our aim was to investigate the protective effects of 2-aminoethyl diphenylborinate (2-APB) ... -
Oxidative stress and total sialic acid levels in sheep naturally infected with pox virus
(Univ Agriculture, 2016)This study was performed to determine the levels of serum nitric oxide (NO), malondialdehyde (MDA), total sialic acid (TSA), and total oxidant capacity (TOC) and total antioxidant capacity (TAC) as well as histopathological ...
