Effects of some pesticides on catalase and glutation s-transferase in cyprinus carpio carpio

Abstract

Free radicals which known reactive oxygen species (ROS) have changing capasity biomolecules like lipids, nucleic acids, considerably reactive and unstabile metabolites. Biological sistems in body developed defence system because of prevent the effect of ROS. This system known ‘antioxidant defence systems’ or shortly ‘antioxidans’. Pesticides may induce oxidative stress, leading to generation of free radicals and cause lipid peroxidation. Due to using of pesticide in agriculture, which fishes are living in polluted freshwaters effect of negative direction. In this study, we investigated some pesticides effects on catalase (CAT) and glutation S-transferase (GST) enzymes obtain from Cyprinus carpio carpio. For this study, today using at agriculture of five different pesticides(2,4- dichloroplenoxy acetic acid dimethylamine salt, fenpropathrin, cypermethrin, lambda-cyhalothrin, deltamethrin) was elected. The inhibitory effect of these pesticides on catalase and glutation s-transferase activity, observed under in vitro experimental conditions. The pesticides used in this study inhibited the catalase and glutation S-transferase activity from Cyprinus carpio carpio to various degrees. These findings observed in vitro could be useful in the understanding of the toxic effects that pesticides elicit on aquatic organisms in vivo.