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dc.contributor.authorUzel, Mehmet Murat
dc.contributor.authorGelişken, Faik
dc.contributor.authorKonrad, Eva
dc.contributor.authorNeubauer, Jonas
dc.date.accessioned2023-10-10T09:58:46Z
dc.date.available2023-10-10T09:58:46Z
dc.date.issued2022en_US
dc.identifier.issn0950-222X / 1476-5454
dc.identifier.urihttps://doi.org/10.1038/s41433-022-02094-3
dc.identifier.urihttps://hdl.handle.net/20.500.12462/13493
dc.descriptionUzel, Mehmet Murat (Balikesir Author)en_US
dc.description.abstractPurpose To analyse the clinical and morphological characteristics of eyes with idiopathic epiretinal membrane (iERM) and foveal herniation (FH). Methods Clinical findings and OCT features of patients with iERM and FH were retrospectively analysed. Primary outcome were changes of the best-corrected-visual-acuity (BCVA) and OCT features from baseline to the last visit. FH patients were divided into two groups based on herniated layers: ganglion cell complex (GCC)-group and sub-GCC-group. Surgical outcome was also assessed. Results In this study, 3882 patients with iERM were screened, of whom 51 (1.3%) were identified with FH. The GCC-group (n = 16) had a better baseline BCVA and thinner central foveal thickness (CFT) in comparison to the sub-GCC-group (n = 35) but without statistical significance (p = 0.330, p = 0.417, respectively). The postoperative BCVA-improvement was similar between the two groups (p = 0.280). Fibrillary surface changes were detected in 42/51 (82.3%) patients, significantly more often in the sub-GCC group (p = 0.020). The baseline BCVA was a predictive factor for the postoperative vision change. Conclusion FH presents with a unique macular morphology in eyes with iERM. Affected eyes experience varying visual disturbances based on the involvement of the inner retinal layers in the foveal herniation. Macular surgery is successful in restoring vision, even though foveal morphology does not fully recover.en_US
dc.description.sponsorshipProjekt DEALen_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.relation.isversionof10.1038/s41433-022-02094-3en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectOphthalmologyen_US
dc.titleClinical and morphological characteristics of patients with idiopathic epiretinal membrane with foveal herniationen_US
dc.typearticleen_US
dc.relation.journalEyeen_US
dc.contributor.departmentTıp Fakültesien_US
dc.contributor.authorID0000-0002-7420-8934en_US
dc.identifier.volumeEarly Access JUN 2022en_US
dc.identifier.startpage1en_US
dc.identifier.endpage4en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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