Güncel Gönderiler: Temel Tıp Bilimleri
Toplam kayıt 322, listelenen: 21-40
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Hibrit gümüş nanoparçacık komplekslerinin sitotoksik ve antilayşmanyal aktivitesinin araştırılması: Leishmania türlerine karşı potansiyel ilaç adayları
(Bilimsel Tıp Yayınevi, 2024)Son yıllarda mevcut ilaçlara dirençli Leishmania türlerinin izole edilmesi, ilaç adayı olabilecek alternatif moleküllerin araştırılmasını zorunlu hale getirmiştir. Bu çalışmada, hibrit gümüş nanoparçacık (AgNP) komplekslerinin ... -
Tehlikeli bir ilişki: Yurt dışı kaynaklı plasmodium falciparum ve salmonella typhi koenfeksiyonu olgusu
(Galenos Yayınevi, 2024)Sıtma, çoğunlukla anofel cinsi dişi sivrisineklerin insanları sokması ile bulaşan paraziter bir hastalıktır. Ülkemizdeki yerli sıtma olgusu bildirimi Dünya Sağlık Örgütü kayıtlarında görülmemekle birlikte, yurt dışı ... -
Volumetric evaluation of substantia nigra in major depressive disorder using atlas-based method
(Effect Publishing Agency ( EPA ), 2024)Aim: The substantia nigra pars compacta (SNc), a vital part of the brain that produces dopamine, is being closely studied due to its potential role in the monoamine hypothesis, which aims to explain the causes of Major ... -
Preconditioning of human umbilical cord mesenchymal stem cells with a histone deacetylase inhibitor: Valproic acid
(Galenos Publishing House, 2024)Background: Mesenchymal stem cells (MSCs) play a key role in regenerative medicine due to their capacity to differentiate into multiple cell lines, regulate the immune system, and exert paracrine effects. The therapeutic ... -
Vegan yaşam tarzını benimseyen bireylerin karşılaştığı psikososyal risk faktörleri
(Balıkesir Üniversitesi Sosyal Bilimler Enstitüsü, 2024)İnsanlar etik, ekolojik, dini veya sağlık temelli motivasyonlar sebebiyle vejetaryen veya vegan beslenmeye geçiş yapmaktadır. Vejetaryen beslenme tarzının kendi içerisinde birçok çeşidi bulunmaktadır. Fakat bu diyet ... -
Ticari doğal aktif bileşenlerin sıtma tedavisindeki etkinliğinin araştırılması
(Türk Mikrobiyoloji Cemiyeti, 2024)Amaç: Bu çalışmada, çeşitli biyolojik aktiviteleri yanında, güçlü antimikrobiyal etkinlikleri gösterilmiş olan kafeik asit, oleik asit ve oleuropin’in in vitro sitotoksik aktivitesi ve in vivo antimalaryal etkinliğinin ... -
Epigenetic enzymes and their mutations in cancer
(Springer Science and Business Media Deutschland GmbH, 2023)Epigenetic mechanisms are crucial for normal development and maintenance of tissue-specific gene expression patterns in mammals. Impaired epigenetic processes can cause alterations in gene function and malignant cellular ... -
Discoidin domain receptor 1 as a promising biomarker for high-grade gliomas
(Wolters Kluwer Medknow Publications, 2023)Background: Two fundamental challenges in the current therapeutic approach for central nervous system tumors are the tumor heterogeneity and the absence of specific treatments and biomarkers that selectively target the ... -
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.815G > A (p.R272Q) or c.1348C > T (p. R450C) in the RHOT1 gene encoding Miro1
(Elsevier, 2023)Fibroblasts from two Parkinson's disease (PD) patients carrying either the heterozygous mutation c.815G > A (Miro1 p.R272Q) or c.1348C > T (Miro1 p.R450C) in the RHOT1 gene, were converted into induced pluripotent stem ... -
Treadmill exercise has healing effects on obesity-induced sexual behavior disorder through kisspeptin and kiss1R expression in male rats
(C M B Assoc, 2023)The basic objective of this study was to examine the possible effects of treadmill exercise on obesity-related sexual behavior disorder in obese male rats and the role of kisspeptin in this effect. The rats were separated ... -
Real-life experiences with galcanezumab disclosed new predictors for response
(Sage Publications Ltd, 2023)Özet bilgisi yok. -
Service quality, outpatient satisfaction and loyalty in community pharmacies in Turkey: A structural equation modeling approach
(Elsevier, 2023)Background: The sustainability of community pharmacy services is dependent on service quality, patient satisfaction, and patient loyalty. While community pharmacies are perceived as medical units in terms of drug dispensing, ... -
The effect of irisin hormone on motor function in thorocal spinal cord injury model
(Wiley, 2023)Özet bilgisi yok. -
Evaluation of mesenchymal stem cells proconditioned with dimethyloxalylglycine with respect to changes in cellular and secretory profiles
(Elsevier Sci Ltd, 2023)Özet bilgisi yok. -
The effect of high-intensity ınterval training (HIIT) on dexamethasone-induced insulin resistance and apo J, lrp2 levels in rats
(Wiley, 2023)Özet bilgisi yok. -
TRPM2 may be involved in high fructose corn syrup-induced anxiety-like behavior in adult male rats
(C M B Assoc, 2023)Excessive high fructose corn syrup (HFCS) consumption is known to cause oxidative stress, which induces transient receptor potential melastatin type 2 (TRPM2) channel gating. Oxidative stress-induced TRPM2 gating is suggested ... -
Therapeutic effects of conditioned medium from human umbilical cord mesenchymal stem cells with/without deferoxamine-preconditioning on the severe type 1 diabetes model in rats
(Elsevier Sci Ltd, 2023)Background & Aim: Type 1 diabetes (T1D) is a T-cell-mediated autoimmune disease characterized by the irreversible destruction of pancreatic -cells. Impaired T-cell balance and cytokine production play a synergistic role ... -
The role of oxytocin receptor gene polymorphisms in sex-specific functional brain network topology
(Wiley, 2023)Özet bilgisi yok. -
High-intensity exercise effect on self care-related behaviors in rodent splash test.
(Wiley, 2023)Özet bilgisi yok.
