• Development and in vivo evaluation of atomoxetine hydrochloride odmts in a nicotine-induced attention deficit hyperactivity disorder (ADHD) model in rats 

  Özbeyen, Atalay; Özyılmaz, Emine Dilek; Deniz, Önal; Pehlivanoğlu, Bilge; Çomoğlu, Tansel (Springer, 2024)

  The current study aimed to evaluate the efcacy of orally administered rapid mini-tablets containing atomoxetine hydrochloride (ODMT) relative to the conventional capsule formulation of atomoxetine hydrochloride (ATO). To ...

• Effects of nutritional status and foods consumed on inflammation and disease activity in patients with rheumatoid arthritis 

  Uysal, Bilal; Şahin, Nilay; Kara, Hayrettin (Multidisciplinary Digital Publishing Institute (MDPI), 2024)

  Background and Objectives: This study investigated the impact of nutritional status and foods consumed on inflammation and disease activity in patients with rheumatoid arthritis (RA). Materials and Methods: We designed ...

• A comparison of pre- and post-treatment cranial MRI characteristics in patients with pediatric epilepsy receiving levetiracetam 

  Aydın, Hilal; Aytaç, Adil; Bülbül, Erdoğan; Yanık, Bahar; Korkut, Oğuzhan; Gülcen, Burak (Multidisciplinary Digital Publishing Institute (MDPI), 2024)

  Background and Objectives: This study was performed for the purpose of assessing whether antiepileptic levetiracetam treatment produces a change in brain volumes in children with epilepsy. To that end, we compared the ...

• Atlas-based structural analysis of prefrontal cortex atrophy in major depressive disorder: Correlations with severity and episode frequency 

  Kökçe, Aybars; Can, Merve Şahin; Karaca, Ömür; Özcan, Emrah; Kuş, İlter (Elsevier Ireland Ltd, 2024)

  Background: Current models of major depressive disorder (MDD) primarily focus on the structural and functional changes in key prefrontal areas responsible for emotional regulation. Among these regions some sections such ...

• Oral microbial dysbiosis in patients with oral cavity cancers 

  Ünlü, Özge; Demirci, Mehmet; Paksoy, Tuğçe; Eden, Arzu Baygül; Tansuker, Hasan Deniz; Dalmızrak, Ayşegül; Aktan, Çağdaş; Şenel, Firdevs (Springer Heidelberg, 2024)

  Objectives The pathogenesis of oral cavity cancers is complex. We tested the hypothesis that oral microbiota dysbiosis is associated with oral cavity cancer. Materials and methods Patients with primary oral cavity cancer ...

• Oncostatin M is related to polycystic ovary syndrome-case control study 

  Çamili, Figen Efe; Akış, Merve; Adalı, Ertan; Hişmioğulları, Adnan Adil; Taşkın, Mine İslimye; Güney, Gürhan; Afşar, Selim (Multidisciplinary Digital Publishing Institute (MDPI), 2024)

  Background: Oncostatin M, a novel adipokine, plays a role in oogenesis, lipogenesis, and inflammation and may contribute to polycystic ovary syndrome pathogenesis and related metabolic problems. Adipokines are believed to ...

• Preconditioning of human umbilical cord mesenchymal stem cells with deferoxamine potentiates the capacity of the secretome released from the cells and promotes immunomodulation and beta cell regeneration in a rat model of type 1 diabetes 

  Işıldar, Başak; Özkan, Serbay; Şahin, Hakan; Erçin, Merve; Oktayoğlu, Selda Gezginci; Koyutürk, Meral (Elsevier, 2024)

  This study aimed to examine the effects of the secretome released by human umbilical cord-mesenchymal stem cells (MSC) as a result of preconditioning with deferoxamine (DFX), a hypoxia mimetic agent, on type 1 diabetes ...

• Evaluation of the association of serum sclerostin and carotid intima media thickness with chronic kidney failure and kidney transplantation 

  Keskiner, Özlem Oğuz; Öztürk, Yasin; Özer, Hakan; Baloğlu, İsmail; Uysal, Saliha; Toker, Aysun; Keskin, Suat; Türkmen, Kültigin (Taiwan Society of Geriatric Emergency and Critical Care Medicine (TSGECM), 2024)

  Purpose: This study aimed to determine the serum sclerostin levels in kidney transplant recipients, dialysis patients, and patients with non-dialysis chronic kidney disease (CKD), and evaluate their associations with carotid ...

• Neuroprotective effects of Sideritis trojana essential oil in AlCl3-induced amnesic rats 

  Hayta, Şükrü; Bulmuş, Özgür; Aksöz, Elif; Uysal, Saliha; Akbaba, Emel (Har Krishan Bhalla and Sons, 2024)

  In this study, the effects of Sideritis trojana essential oil on memory, anxiety, and depression were investigated in rats subjected to AlCl3-induced dementia. The major constituents of S. trojana essential oil were analyzed ...

• In vitro and in silico investigations of the pro-apoptotic activity of Opuntia ficus-indica cladode extracts against K562 cells 

  Öncül, Şule; Becer, Eda; Tiber, Pınar Mega; Teralı, Kerem; Aykac, Asli (Walter De Gruyter GMBH, 2024)

  Objectives: Cladodes of Opuntia ficus-indica (OFI) are thought to be an excellent source of bioactive compounds, making them an aspirant for the manufacture of health-promoting compounds. This study aims at exploring the ...

• Could hepcidin be a new biomarker in patients with idiopathic pulmonary fibrosis (IPF)? 

  Yılmaz, Gülçin; Çoban, Hikmet; Sarıoğlu, Nurhan; Erel, Fuat; Yılmaz, Merve Akış; Çolak, Mustafa; Şenel, Merve Yumrukuz; Hişmioğulları, Adnan Adil (MDPI, 2024)

  Hepcidin is a biomarker produced by hepatocytes in chronic disease anemia and is known to increase during chronic inflammation. This study compares the hepcidin levels in idiopathic pulmonary fibrosis (IPF) patients and ...

• Effects of chronic intermittent cold stress on anxiety-depression-like behaviors in adolescent rats 

  Değirmenci, Merve Deniz; Çalışkan, Hasan; Güneş, Emel (Elsevier, 2024)

  Stress, which triggers numerous physiological and behavioral responses in the organism, is a significant risk factor that contributes to the development of psychiatric disorders such as depression and anxiety. This study ...

• Darbepoetin alpha has an anxiolytic and anti-neuroinflammatory effect in male rats 

  Çalışkan, Hasan; Önal, Deniz; Nalçacı, Erhan (BMC, 2024)

  Aims We aimed to investigate the anxiolytic effect of darbepoetin alpha (DEPO), an erythropoietin derivative, in a neuroinflammation model regarding different behaviors and biological pathways. Methods Forty adult male ...

• Effect of high-intensity interval training on self-care and anxiety-like behaviors in naive rats 

  Çalışkan, Hasan; Karakaya, Dilara; Koçak, Seda; Ömercioğlu, Göktuğ; Baştuğ, Metin (Springer, 2024)

  Self-care behavior covers individual's health, life and well-being to maintain the necessary activities. The aim of this study is to examine the self-care and possible anxiolytic efects of high-intensity interval exercise ...

• Comparative analysis of effects of conditioned mediums obtained from 2D or 3D cultured mesenchymal stem cells on kidney functions of diabetic rats: Early intervention could potentiate transdifferentiation of parietal epithelial cell into podocyte precursors 

  Özkan, Serbay; Işıldar, Başak; Şahin, Hakan; Saygı, Halil İbrahim; Konukoğlu, Dildar; Koyutürk, Meral (Elsevier, 2024)

  Aim: The secretome of mesenchymal stem cells (MSCs) could be a potential therapeutic intervention for diabetes and associated complications like nephropathy. This study aims to evaluate the effects of conditioned ...

• Effects of coenzyme Q10, fullerene C60, and αlpha-lipoic acid on histomorphometric, antiapoptotic and ınsulin expression in pancreatic tissue of rats exposed to bisphenol A 

  Çeribaşı, Songül; Yüce, Abdurrauf; Bulmuş, Özgür (Prof.Dr. Mustafa İssi, 2024)

  The aim of this study was to determine the morphometric changes in the pancreas, apoptosis related pancreatic damage, and differences in insulin expression in male rats exposed to low doses of BPA from early pubertal ...

• Evaluation of serum magnesium levels in patients with the diagnosis of depressive disorder applied to a psychiatry clinic: A retrospective study 

  Altunöz, Sinan; Baykan, Hayriye; Baykan, Özgür (Balıkesir Üniversitesi, 2024)

  Objective: The role of magnesium in the pathophysiology of depression has increased the interest in magnesium. Therefore, in this study, we aimed to evaluate serum magnesium levels in patients diagnosed with depressive ...

• The relationship between physical activity and cognition in Kırşehir Ahi Evran University medical faculty students 

  Koçak, Seda; Çalışkan, Hasan; Karakullukçu, Serdar; Pektaş, Ferhat (Ahi Evran Üniversitesi Tıp Fakültesi, 2024)

  Purpose: Due to the difficulty and intensity of medical school education, medical students often lead a sedentary lifestyle. As seen in different methodological studies, physical activity affects cognitive functions. Few ...

• Choice of empirical treatment in patients with wound infection 

  Duran, Hülya; Çeken, Nihan; Atik, Tuğba Kula; Yeniiz, Esma (Marmara Üniversitesi, 2024)

  Objective: We aimed to determine the distribution of infectious agents in wound culture specimens, their resistance rates, and to evaluate empirical treatment choices in wound infections. Methods: Wound culture results of ...

• Protective effect of pomegranate juice on lead acetate-induced liver toxicity in male rats 

  Pekmez, Hıdır; Annaç, Ebru; Bulmuş, Özgür; Zencirci, Büşra; Aydın, Merve; Aydın, Ali (Pera Yayıncılık, 2024)

  Objective: Lead has been reported to cause oxidative stress in liver tissues and cause histopathological changes. Studies have shown that pomegranate juice has antioxidant properties that prevent oxidative stress. In ...

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