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dc.contributor.authorGünaydın, Zeki Yüksel
dc.contributor.authorKaragöz, Ahmet
dc.contributor.authorBektaş, Osman
dc.contributor.authorKaya, Ahmet
dc.contributor.authorKırış, Tuncay
dc.contributor.authorErdoğan, Güney
dc.contributor.authorIşık, Turgay
dc.contributor.authorAyhan, Erkan
dc.date.accessioned2019-05-16T19:32:24Z
dc.date.available2019-05-16T19:32:24Z
dc.date.issued2016
dc.identifier.issn2149-2263
dc.identifier.urihttps://hdl.handle.net/20.500.12462/3849
dc.descriptionIşık, Turgay (Balikesir Author)en_US
dc.description.abstractObjective: Although various risk stratification models are available and currently being used, the performance of these models in different populations is still controversial. We aimed to investigate the relation between the Framingham and SCORE models and the presence and severity of coronary artery disease, which is detected using the SYNTAX score.Methods: The observational cross-sectional study population consisted of 227 patients with a mean age of 63.3±9.2 years. The patients were classified into low- and high-risk groups in the Framingham and SCORE models separately. Following coronary angiography, the patients were classified into SYNTAX=0 (SYNTAX score 0), low SYNTAX (SYNTAX score 1-22), and high SYNTAX (SYNTAX score>22) groups. The relation between the risk models and SYNTAX score was evaluated by student t test, Mann-Whitney U test or Kruskal-Wallis test and Receiver operating characteristic analysis were used to detect the discrimination ability in the prediction of SYNTAX score>0 and a high SYNTAX score.Results: Both the Framingham and SCORE models were found to be effective in predicting the presence of coronary artery disease, and neither of the two models had superiority over each other [AUC=0.819 (0.767, 0.871) vs. 0.811 (0.757, 0.861), p=0.881]. Furthermore, both models were also effective in predicting the extent and severity of coronary artery disease [AUC=0.724 (0.656, 0.798) vs. 0.730 (0.662, 0.802), p=0.224]. When the subgroups were analyzed, the SCORE model was found to be better in predicting coronary artery disease extent and severity in subgroups of men and diabetics {[AUC=0.737 (0.668, 0.844) vs. 0.665 (0.560, 0.790), p=0.019], [AUC=0.733 (0.684, 0.798) vs. 0.680 (0.654, 0.750) p=0.029], respectively).Conclusion: In addition to their role in predicting cardiovascular events, the use of the Framingham and SCORE models may also have utility in predicting the extent and severity of coronary artery disease. The SCORE risk model has a slightly better performance than the Framingham risk model.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSYNTAX Scoreen_US
dc.subjectFramingham Risk Scoreen_US
dc.subjectSCOREen_US
dc.titleComparison of the Framingham risk and SCORE models in predicting the presence and severity of coronary artery disease considering SYNTAX scoreen_US
dc.typearticleen_US
dc.relation.journalThe Anatolian Journal of Cardiologyen_US
dc.contributor.departmentTıp Fakültesien_US
dc.identifier.volume16en_US
dc.identifier.issue6en_US
dc.identifier.startpage412en_US
dc.identifier.endpage418en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US


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