Güncel Gönderiler: Tıp Fakültesi
Toplam kayıt 1708, listelenen: 201-220
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Investigation of the anticancer mechanism of monensin via apoptosis-related factors in SH-SY5Y neuroblastoma cells
(Wiley, 2023)Monensin is an ionophore antibiotic that inhibits the growth of cancer cells. The aim of this study was to investigate the apoptosis-mediated anticarcinogenic effects of monensin in SH-SY5Y neuroblastoma cells. The effects ... -
The use of radiomics and machine learning for the differentiation of chondrosarcoma from enchondroma
(Wiley, 2023)Purpose: To construct and compare machine learning models for differentiating chondrosarcoma from enchondroma using radiomic features from T1 and fat suppressed Proton density (PD) magnetic resonance imaging (MRI). Methods: ... -
The effect of intravenous lipid emulsion (ILE) on the pharmacokinetic/toxicokinetic dispositions of ivermectin and carprofen in rabbits
(Springer, 2023)Intravenous lipid emulsion (ILE) has been widely used as an effective antidote in both veterinary and human medicine for the treatment of acute intoxications caused by drugs and pesticides with high lipid solubility. This ... -
Effect of the ureteral access sheath size on acute kidney injury biomarkers in retrograde intrarenal surgery: A prospective, randomized study
(Karger, 2023)Introduction: The aim of the study was to investigate the effect of the diameter of the ureteral access sheath (UAS) used during RIRS on kidney injury based on acute kidney injury (AKI) biomarkers. Methods: This prospectively ... -
Evaluation of serum telomerase activity in normal-weight young girls with polycystic ovary syndrome and its relation to metabolic parameters
(Walter De Gruyter GMBH, 2023)Objectives: This study investigated the discriminative value of serum telomerase levels in polycystic ovary syndrome (PCOS) and its relation to metabolic parameters.Methods: Patients aged 16-23 years old who visited an ... -
Use of hyaluronic acid matrix in dorsal augmentation rhinoplasty
(Taylor & Francis Ltd, 2023)Augmentation rhinoplasty sometimes is required for patients with saddle nose deformity caused by failed rhinoplasty or facial trauma; finding appropriate grafting material remains a significant problem for this procedure. ... -
Modulation of melatonin receptors regulates reproductive physiology: The impact of agomelatine on the estrus cycle, gestation, offspring, and uterine contractions in rats
(Acad Sciences Czech Republic, 2023)Agomelatine is a pharmaceutical compound that functions as an agonist for melatonin receptors, with a particular affinity for the MT1 and MT2 receptor subtypes. Its mode of action is integral to the regulation of diverse ... -
Protective effects of Silymarin on testicular torsion/detorsion in rats
(Verduci Publisher, 2023)OBJECTIVE: The present research aimed to study the possible protective effects of Silymarin on testicular I/R injury in a rat model evaluated through histopathology and biochemical parameters. MATERIALS AND METHODS: This ... -
A cross-cultural analysis for plastic waste perception of students from Romania and Turkey
(MDPI, 2023)The article brings to attention a cross cultural model related to the perception of students in relation to the current problem of plastic waste. To create the model, a questionnaire was applied online in two countries at ... -
Emotion dysregulation and affective temperaments in opioid use disorder: a 1-year follow-up study
(Routledge Journals, Taylor & Francis Ltd, 2023)BackgroundOpioid use disorder (OUD) remains a significant public health challenge with high recurrence rates and varied long-term outcomes. Affective temperament and emotion regulation have been identified as influencing ... -
Neglecting the neglected: Tobacco cessation support is 'essential' for the management of asthma and COPD
(European Respiratory Soc Journals Ltd, 2023)Introduction: Asthma and COPD management have a broad framework, and smoking cessation plays an essential role. We aimed to examine the management of asthma and COPD patients not only for inhaler treatment options but also ... -
Can electrodiagnostic tests be omitted from surgical decision-making for typical carpal tunnel syndrome? - A randomized controlled trial
(Wolters Kluwer Medknow Publications, 2023)Background: Although carpal tunnel syndrome (CTS) is common and frequently seen in daily practice, diagnostic criteria remain the subject of debate. Some authors consider electrodiagnostic tests as essential, whereas others ... -
Treadmill exercise improves behavioral and neurobiological alterations in restraint-stressed rats
(Springer Nature, 2023)Stress is a state that is known to impact an organism's physiological and psychological balance as well as the morphology and functionality of certain brain areas. In the present work, chronic restraint stress (CRS) model ... -
Development and validation of liquid chromatography/stable isotope-dilution tandem mass spectrometry method for measurement of dexamethasone, total cortisol and free cortisol in human plasma
(Dokuz Eylul Univ Inst Health Sciences, 2023)Background Cortisol plays a role in the regulation of metabolic homeostasis. Dexamethasone is a powerful synthetic glucocorticoid that acts as an anti-inflammatory and immunosuppressive agent. Plasma free cortisol, which ... -
Postoperative alpha angle seems to be important for the achievement of clinical significance at a minimum 5-year follow-up after primary hip arthroscopy
(Oxford Univ Press, 2023)The purpose of the present study was to clarify whether there is an association of postoperative alpha value with functional scores or progression of osteoarthritis at X-rays at the midterm after arthroscopic treatment of ... -
Therapeutic potential of mesenchymal stem cell-derived conditioned medium for diabetes mellitus and related complications
(Wiley, 2023)Diabetes mellitus (DM) is one of the most life-threatening metabolic disorders, with 9% of the global prevalence, and it is estimated to be rising to 12.2% in 2045. Currently, there is no definitive treatment for DM. ... -
Protective effect of pomegranate juice on lead acetate-induced liver toxicity in male rats
(Pera Yayıncılık Hizmetleri, 2023)Objective: Lead has been reported to cause oxidative stress in liver tissues and cause histopathological changes. Studies have shown that pomegranate juice has antioxidant properties that prevent oxidative stress. In this ... -
Effects of conditioned mediums collected from 2d or 3d cultured mscs on kidney functions of rats with autoimmune diabetes induced with streptozocin
(Oxford Univ Press, 2023)Background and Aims: The main mechanism of therapeutic action of mesenchymal stem cells (MSCs) could be resulted from their secretome content rather than their direct differentiation into damaged cells [1, 2]. Preconditioning ... -
Optimal timing and outcome of transforaminal epidural steroid injection for the management of radicular pain due to extruded lumbar disc herniation
(Turkish Neurosurgical Soc, 2023)AIM: To evaluate the optimal timing and outcome of fluoroscopically guided transforaminal epidural steroid injections (TFESI) for the management of radicular pain due to extruded lumbar disc herniation (LDH). MATERIAL and ... -
Effectiveness of lactate clearance to predict in-hospital mortality in patients with upper gastrointestinal bleeding
(Coll Physicians & Surgeons Pakistan, 2023)Objective: To determine the performance of lactate clearance to predict prognosis in patients with upper gastrointestinal bleeding (UGIB).Study Design: Observational study.Place and Duration of the Study:Department of ...